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Disc Herniation clinical trials

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NCT ID: NCT06275529 Not yet recruiting - Low Back Pain Clinical Trials

Evaluation of Transforaminal Epidural Steroid Injection in Radicular Low Back Pain According to MSU Classification

Start date: March 15, 2024
Phase: N/A
Study type: Interventional

Low back pain is a common disease in all ages and it effects seriously quality of life. Medical treatment,interventional methods and surgery are the treatment options. Transforaminal epidural steroid injections (TFSI) is one of the interventional method for radiculopathy with low back pain. Michigan State University(MSU) classification is a MRI based disc herniation classification. It helps to classified disc herniation in types, places and sizes. The aim of this study to evaluate the pain and oswestry disability index in patients who have radiculopathy with low back pain, undergone TFSI according to MSU classification.

NCT ID: NCT06178939 Not yet recruiting - Lung Neoplasms Clinical Trials

Effects of Cognitive Intervention Therapy on Postoperative Delirium

Start date: December 2023
Phase: N/A
Study type: Interventional

This study is a prospective, single-center, randomized controlled trial to compare whether applying cognitive intervention therapy before and after surgery in elderly patients aged 65 years or older undergoing non-cardiac surgery can reduce the incidence of postoperative delirium compared to conservative treatment.

NCT ID: NCT06141551 Active, not recruiting - Disc Herniation Clinical Trials

Intradural Disc Herniation: a Case Report and Review of Complications

Start date: October 1, 2023
Phase:
Study type: Observational

This observational study collects clinical data as well as pathological reports from a patient with an intradural disc herniation, reports on the course of the patient's recovery through surgical treatment, summarizes the complications of this type of disease, and provides new ideas for improving the chances of preoperative diagnosis.

NCT ID: NCT06046781 Completed - Surgery Clinical Trials

Exercise After Lumbar Disc Herniation Surgery

Start date: April 1, 2023
Phase: N/A
Study type: Interventional

Physical therapy and rehabilitation may improve low back pain and quality of life after lumbar disc herniation. But there is not any agreement of its optimal start time, and rehabilitative methods. This study evaluates the effects of early and late rehabilitation to the low back pain and quality of life following unilateral microdiscectomy.

NCT ID: NCT06023719 Recruiting - Clinical trials for Disk Herniated Lumbar

Safety And Performance Of Disc Care To Prevent Lumbar Disc Herniation Recurrence

ACE-2
Start date: November 2023
Phase: N/A
Study type: Interventional

The goal of this clinical investigation is to learn about DISC Care, an Hernia Blocking System, in patients who have undergone lumbar disc hernia surgery. The main questions it aims to answer are: - if the implant (DISC Care) prevents disc herniation recurrence - if DISC Care is a safe device Participants will be implanted with DISC Care and followed up for two years (7 visits).

NCT ID: NCT06006377 Completed - Neck Pain Clinical Trials

Investigation of the Efficacy of Treatments With Backup Device in Spine Pathologies

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Our aim in this study is to examine the effectiveness of the Backup spine health device in spinal problems and compare it with traditional physical therapy methods.

NCT ID: NCT05999565 Not yet recruiting - Neck Pain Clinical Trials

Investigation of the Effect of Motor Imagery Training in Individuals With Cervical Discogenic Pain

Start date: January 4, 2024
Phase: N/A
Study type: Interventional

In this study, motor control exercises including cervical region, upper extremity and scapular region muscles will be applied routinely in individuals with chronic neck pain. The application will been investigating, called motor imagery training, will been carried out together with motor control exercises.

NCT ID: NCT05808140 Recruiting - Disc Herniation Clinical Trials

Fluorescence Imaging With Indocyanine Green(ICG) in Endoscopic Spinal Surgery

Start date: April 11, 2023
Phase: Phase 1/Phase 2
Study type: Interventional

In endoscopic spinal nerve root decompression surgery, the intraoperative nerve exploration is time-consuming and critical. According to statistics, the incidence of nerve root injury under spinal endoscope is 1.8-2.5%. Damage to nerve roots may lead to postoperative sensory retardation and motor weakness, thereby impairing the physical function of patients. A real-time auxiliary intraoperative nerve identification technology is necessary. In this prospective, open-label, randomized, parallel controlled trial, 40 patients who undergo endoscopic spinal surgery are included. Subjects are randomly divided into control group and low, medium and high Indocyanine green(ICG) preoperative administration experimental group. Standard endoscopic spinal surgery is performed in the control group. Patients in the experimental group received an intravenous injection of ICG before surgery, and a standard endoscopic spinal surgery is performed with the use of a fluoroscopic endoscopic surgical imaging system to assist the surgeon in identifying and protecting the nerve roots. The main objectives of this experiment are (i) to explore the safety and feasibility of ICG fluorescence imaging to assist in nerve root identification during endoscopic spinal surgery and (ii) the effectiveness of this technique for endoscopic search for nerve roots. The secondary objective is to explore the optimal ICG dosing regimen.

NCT ID: NCT05803954 Completed - Clinical trials for Cervical Radiculopathy

Mobilization With Movement vs. Neural Mobilization on Nerve Root Function in Patients With Cervical Radiculopathy

Start date: March 31, 2023
Phase: N/A
Study type: Interventional

This study will be conducted to compare the effect of sustained natural apophyseal glides (SNAGS) versus neural mobilization on clinical outcomes such as 1- nerve root function in the form of: (A) peak to peak amplitude; (B) latency; (C) F wave. 2- pain pressure threshold (PPT) and 3- Neck disability index (NDI) in patients with cervical disc (C5-C6 and/or C6-C7) herniation. Seventy two patients from both gender with cervical disc (C 5-C 6 and/or C 6- C7) herniation with both sensory and motor nerve affections will be recruited for this study following referral from an experienced neurologist and confirmed diagnosis by MRI. The patients' age will range between 20-50 years, body mass index (BMI) from 18 to 25 kg/cm2. The patients will be assigned randomly by permuted block to three equal groups; group (A) will receive SNAGS in addition to traditional therapy, group (B) will receive neural mobilization in addition to traditional therapy and group (C) will receive traditional therapy. peak to peak amplitude, nerve latency and F wave will be measured by electromyography, , pressure pain threshold will be measured by commander algometer. Neck disability will be measured by Arabic neck disability index.

NCT ID: NCT05753579 Completed - Clinical trials for Intervertebral Disc Displacement

Is Regression Possible in Lumbal Disc Herniation With Spinal Mobilization Applications?

Start date: January 18, 2021
Phase: N/A
Study type: Interventional

Spinal mobilization methods are passive maneuvers that are made lighter and do not exceed the physiological range of motion in order to increase joint mobility. Mobilization applications are easier and safer than manipulation applications involving forceful pushing. Although there are many literatures reporting the therapeutic efficacy of long-term mobilization applications on LDH, there is no study on the effect of applications on radiological findings of LDH. In the light of the information mentioned above, the aim of this study is; To examine the effect of mobilization applications on radiological findings and functional level in patients with LDH