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NCT06420791 Clinical Trial

The Dual Impact of Cirrhosis on Transplantation for Hepatocellular Carcinoma：a Two-center Retrospective Cohort Study in China

Hepatocellular Carcinoma Clinical Trial

Official title:
The Dual Impact of Cirrhosis on Transplantation for Hepatocellular Carcinoma：a Two-center Retrospective Cohort Study in China

Clinical Trial Details — Status: Completed

Administrative data
NCT number NCT06420791
Other study ID # CT2024-ZJU-OBS9
Secondary ID
Status Completed
Phase
First received
Last updated
Start date February 28, 2024
Est. completion date May 6, 2024

Study information
Verified date May 2024
Source Zhejiang University
Contact n/a
Is FDA regulated No
Health authority
Study type Observational

Clinical Trial Summary

Background: This study aims to investigate the correlation between cirrhosis and hepatocellular carcinoma (HCC) recurrence after Liver Transplantation. Methods: The study retrospectively collected data enrolled from 519 HCC patients who underwent liver transplantation from two center(the First Affiliated Hospital, Zhejiang University School of Medicine and Shulan (Hangzhou) Hospital, January 2015 to December 2020), Based on important variables, 1:3 propensity score matching (PSM) were performed respectively.

Recruitment information / eligibility
Status Completed
Enrollment 1
Est. completion date May 6, 2024
Est. primary completion date May 3, 2024
Accepts healthy volunteers No
Gender All
Age group N/A and older
Eligibility Inclusion Criteria: The patients undergoing liver transplantation for HCC from January 2015 to December 2020. Exclusion Criteria: Re-transplantation or combined liver-kidney transplantation; incomplete laboratory or clinical data; death within 90 days.

Study Design

Related Conditions & MeSH terms

Locations
Country Name City State
China Zhejiang University school of Medicine Hangzhou Zhejiang

Sponsors (1)
Lead Sponsor Collaborator
Xiao Xu

Country where clinical trial is conducted

China, 

Outcome
Type Measure Description Time frame Safety issue
Primary The overall survival rate was evaluated by follow-up investigation and outpatient review 2-5 years
Secondary The tumor-free survival rate was evaluated by follow-up investigation and outpatient review 2-5 years
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