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Clinical Trial Summary

NLP-KAT-101 is a Phase 1/2a dose escalation and expansion study to investigate the safety, tolerability, PK, and preliminary efficacy of oral + intratumoral (IT) KAT in subjects with HCC.


Clinical Trial Description

Phase 1 will identify the optimal dose for oral alone, IT alone and the recommended Phase 2 dose (RP2D) dose for oral + IT together. Once the RP2D is identified, additional subjects will be enrolled into Phase 2a (dose-expansion) to further investigate the efficacy and safety of oral + IT KAT at the RP2D. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05603572
Study type Interventional
Source NewG Lab Pharma
Contact
Status Active, not recruiting
Phase Phase 1/Phase 2
Start date November 1, 2022
Completion date November 2025

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