Hepatocellular Carcinoma Clinical Trial
Official title:
Factors Affecting Post-treatment Outcomes in Patients With Hepatocellular Carcinoma
EASL and mRECIST criteria differ from each other in terms of the number of target lesions (all versus < = 2) and calculation method (bidimensional versus unidimensional). Therefore, the investigators aimed to retrospectively analyze and compare the clinical outcomes among patients with hepatocellular carcinoma who were treated with different modalities of therapy according to the BCLC classification, and detect the possible predictors of post-treatment outcomes.
Background:
EASL and mRECIST criteria differ from each other in terms of the number of target lesions
(all versus < = 2) and calculation method (bidimensional versus unidimensional). Therefore,
the investigators aimed to retrospectively analyze and compare the clinical outcomes among
patients with hepatocellular carcinoma (HCC) who were treated with different modalities of
therapy according to the BCLC classification, and detect the possible predictors of
post-treatment outcomes.
Methods:
This work was conducted at the departments of tropical medicine and gastroenterology,
internal medicine, and general surgery. This study included patients that matched our
eligibility criteria for a period of five years started from June 2015 to May 2020. The study
purpose was to retrospectively analyze the clinical outcomes among patients with HCC who were
treated with different modalities of therapy according to the BCLC classification, and detect
the possible predictors of post-treatment favorable outcomes. The data of the patients were
extracted and retrospectively reviewed from the patients' records and the databases of both
hospitals (SUH and SOI).
During the period of recruitment, 407 patients diagnosed with HCC admitted to our departments
and followed-up attending outpatient clinics, Sohag University Hospitals, over a 5 years
period.
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