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Clinical Trial Summary

The study is aimed to the test efficacy and safety of neoantigen-primed dendritic cell (DC) cell vaccine therapy for postoperative locally advanced gastric cancer, hepatocellular carcinoma, lung cancer and colorectal cancer, and to explore the biomarkers related to efficacy and adverse event.


Clinical Trial Description

Postoperative patients with pathological confirmed locally advanced gastric cancer, hepatocellular carcinoma, non-small cell lung cancer and colorectal cancer with standard adjuvant treatment are enrolled. This is a prospective exploratory trial. Patients' tumor tissues are subsequent to whole exosome sequencing and possible neoantigens are identified. DC is in vitro primed with synthesized peptides. Both adverse events and responses are recorded. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04147078
Study type Interventional
Source Sichuan University
Contact Qiu Li
Phone +86 028-85422589
Email liqiu@scu.edu.cn
Status Recruiting
Phase Phase 1
Start date June 1, 2019
Completion date June 1, 2026

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