Hepatocellular Carcinoma Clinical Trial
Official title:
A Phase 1 Open-label Dose Escalation Study of CGX1321 in Subjects With Advanced Gastrointestinal Tumors
This is a multi-center, open label, repeat dose, Phase 1 study consisting of a Dose Escalation Phase and a Dose Expansion Phase to evaluate safety, pharmacokinetics, and clinical activity.
The purpose of the Dose Escalation Phase is to examine the safety and determine the maximum
tolerated dose of CGX1321 when administered to subjects with advanced GI tumors that have
relapsed or are refractory to or not considered medically suitable to receive standard of
care treatment.
Once the dose is identified in the Dose Escalation Phase, the Dose Expansion Phase will
start. The purpose of the Dose Expansion Phase is to continue to examine the safety and
confirm the final Phase 2 dose of CGX1321 when administered to subjects with advanced GI
tumors who meet the entry criteria.
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