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Immunological Response After Ablative Therapy in the Liver — IRAL  

Hepatocellular Carcinoma Clinical Trial

Official title:
Comparison of Immunological Response After Microwave Ablation and Irreversible Electroporation of Hepatocellular Carcinoma

Clinical Trial Summary

Local ablative treatment of Hepatocellular Carcinoma is performed primary on patients not eligible for liver transplant or liver resection. At our Hospital two different methods are used: Microwave ablation, where the tumor cells are heated up and killed, and Irreversible electroporation, where the tumor cells are exposed to an electrical field and nano-pores are formed in the cell membranes and the cells go into apoptosis (programed cell death). Previous studies have shown effects on the immune system after ablative therapies. The purpose of this study is to compare the immunological response after the wo different methods of killing the tumor cells.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT03040453
Study type Interventional
Source Karolinska Institutet
Contact
Status Withdrawn
Phase N/A
Start date January 1, 2017
Completion date September 30, 2018
View Details
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