Hepatocellular Carcinoma Clinical Trial
Official title:
A Randomized Controlled Study on the Effect of S-Adenosyl Methionine Treatment on Anti-tumor Recurrence After Curative Resection of Hepatocellular Carcinoma
The aim of this study is to explore the effect of S-Adenosyl Methionine on recurrence after curative resection of Hepatocellular Carcinoma.
Hepatocellular carcinoma (HCC) is now a major health problem. Although the recent advances
in treatment of HCC have significantly improved the prognosis of patients with HCC, the
overall survival rate is still unsatisfactory; the 5-year survival rate is only 50-70% even
after curative treatment such as hepatic resection and percutaneous radiofrequency ablation.
One of the reasons for the poor prognosis of HCC is its high rate of
recurrence.However,anti-relapse treatment remains a pressing work to do.
In recent years, some study reported that S-Adenosyl Methionine had an impact on promoting
apoptosis and inhibiting the growth on breast cancer, colon cancer,gastric cancer and liver
cancer in vitro and vivo.
In this study, we aim to examine whether S-Adenosyl Methionine have an effect on improving
patients' recurrence after curative resection of Hepatocellular Carcinoma.
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Allocation: Randomized, Endpoint Classification: Safety/Efficacy Study, Intervention Model: Parallel Assignment, Masking: Open Label, Primary Purpose: Treatment
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