Hepatocellular Carcinoma Clinical Trial
Official title:
Response Assessment for External Beam Radiation Therapy in Spinal Metastasis of Hepatocellular Carcinoma (HCC): Usefulness of Diffusion-Weighted Magnetic Resonance (MR) Imaging as A Functional Imaging
Recently, diffusion-weighted (DW) MR imaging has widened its application on various
oncologic applications. Especially, it is expected the DW MRI could provide valuable
information about early response evaluation after treatment using rapid apparent diffusion
coefficient (ADC) value change. It has demonstrated potential usefulness in response
evaluation in the liver tumors after treatments such as transarterial chemoembolization
(TACE) and radiation therapy (RT). Furthermore, it is a functional imaging technique that
does not require a contrast agent, it can be safely used in patients with renal
insufficiency or other medical contraindications for contrast agents.
The optimal assessment of early response of RT could provide one of the most important
information to prescribe patient and cancer specific RT dose. It might be also important in
palliative RT of HCC bone metastasis which is related with painful aggressive mass
formation.
This study is performed to evaluate the usefulness of DW MRI in early response evaluation
after RT for HCC bone metastasis.
n/a
Intervention Model: Single Group Assignment, Masking: Open Label, Primary Purpose: Diagnostic
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