Intravascular Ultrasound for Hepatocellular Carcinoma Staging

Hepatocellular Carcinoma Clinical Trial

Official title:

Intravascular Ultrasound for the Staging of Hepatocellular Carcinoma: a Pilot Study

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT00474734
• Other study ID #: 07-063
• Status: Recruiting
• Phase: N/A
• First received: May 15, 2007
• Last updated: May 16, 2007
• Start date: May 2007
• Est. completion date: September 2007

Study information

• Verified date: May 2007
• Source: University Hospital, Geneva
• Contact: Antoine Hadengue, Prof.
• Phone: +41 22 37 29 340
• Email: antoine.hadengue[@]hcuge.ch
• Is FDA regulated: No
• Health authority: Switzerland: Swissmedic
• Study type: Observational

Clinical Trial Summary

To diagnose hepatocellular carcinoma (HCC) and to determine the extent of the disease, a triphasic CT scan or a magnetic resonance imaging are required. The characterization of hepatic nodules is more difficult when the HCC lesions have a diameter of less than 2 cm.

Since accuracy in the assessment of the number and the size of HCC nodules, as well as of the invasion of blood vessels is crucial to determine outcome after liver transplantation due to tumour recurrence, there is a need for techniques with a higher definition potential.

As a consequence, to improve outcome and to optimize organ allocation, patients on the liver transplantation waiting list might benefit from intravascular ultrasound as an additional examination to complete the pre-transplant tumour staging process.

Other known NCT identifiers

• NCT00472979

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 0
• Est. completion date: September 2007
• Accepts healthy volunteers: No
• Gender: Both
• Age group: 18 Years to 65 Years

Eligibility

Inclusion Criteria:

• hepatocellular carcinoma nodules

• patient on liver transplantation waiting list

• written informed consent

Exclusion Criteria:

• thrombosis of hepatic veins or vena cava

Study Design

Observational Model: Defined Population, Primary Purpose: Screening, Time Perspective: Longitudinal

Related Conditions & MeSH terms

• Carcinoma
• Carcinoma, Hepatocellular
• Hepatocellular Carcinoma

Intervention

Device:
• Intravascular ultrasound of the liver

Locations

Country	Name	City	State
Switzerland	University Hospital Geneva	Geneva

Sponsors (1)

Lead Sponsor	Collaborator
University Hospital, Geneva

Country where clinical trial is conducted

Switzerland,