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Hepatocellular Carcinoma clinical trials

View clinical trials related to Hepatocellular Carcinoma.

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NCT ID: NCT02558205 Withdrawn - Clinical trials for Hepatocellular Carcinoma

Correlation Between CT Perfusion and Post Y-90 TARE PET/CT Dosimetry

Start date: July 2015
Phase:
Study type: Observational

The purpose of this study is to see if it is possible to establish a relationship between the blood flow and blood volume of liver tumors from CT body perfusion and the radiation dose deposited in the tumors from the radioembolization treatment as measured by PET/CT. The study will do this by: 1. Measuring the blood flow and blood volume of tumors in the imaging data from a CT body perfusion 2. Measuring the radioactivity in the tumors after the radioembolization treatment using PET/CT and then calculating the dose deposited in the tumor 3. Using statistical analysis to assess the relationship between the dose and the perfusion parameters In addition, the research may help develop a method for calculating the dose of radioembolization to be delivered to a liver tumor(s) using blood volume and blood flow data obtained from the CT body perfusion scans.

NCT ID: NCT02534337 Withdrawn - Clinical trials for Hepatocellular Carcinoma

Gemcitabine Plus Oxaliplatin Versus Oxaliplatin Plus Fluorouracil/Leucovorin for Hepatocellular Carcinoma

Start date: September 2015
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine that Gemcitabine(GEM) plus oxaliplatin(OXA) (GEMOX) is superior to Oxaliplatin Plus Fluorouracil/Leucovorin(FOLFOX4) in prolonging progression-free survival(PFS) in patients with Advanced Hepatocellular Carcinoma.

NCT ID: NCT02527772 Withdrawn - Clinical trials for Hepatocellular Carcinoma

Liposomal Doxorubicin Plus Gemcitabine Versus Oxaliplatin Plus Fluorouracil/Leucovorin for Hepatocellular Carcinoma

LD-FOX4/HCC
Start date: September 2015
Phase: Phase 2/Phase 3
Study type: Interventional

The purpose of this study is to determine that Liposomal Doxorubicin(LD) plus Gemcitabine(GEM) is superior to Oxaliplatin(OXA) Plus Fluorouracil/Leucovorin(FOLFOX4) in prolonging progression-free survival(PFS) in patients with Advanced Hepatocellular Carcinoma.

NCT ID: NCT02289300 Withdrawn - Clinical trials for Hepatocellular Carcinoma

A Study to Evaluate a Study Drug, DCB-BO1202, for Alleviating Liver Fibrosis in Liver Cancer Patients

Start date: January 2020
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine whether an investigational drug DCB-BO1202 is effective and safe in the treatment of liver fibrosis in HBV patients having experienced intermediate stage hepatocellular carcinoma (HCC)

NCT ID: NCT02174575 Withdrawn - Clinical trials for Hepatocellular Carcinoma

Anesthetic Agents and Acute Kidney Injury After Liver Resection Surgery

Start date: July 2014
Phase: Phase 4
Study type: Interventional

- It has been shown that patients who undergo liver resection surgery are at high risk for postoperative acute kidney injury (AKI). - Sevoflurane may increase the risk for postoperative AKI because of production of compound-A. - Therefore, we have planned to investigate the effects of different anesthetic agents on postoperative renal function. - Patients undergoing liver resection surgery are randomized into 2 groups. - One of the groups receives sevoflurane and the other group receives desflurane. - Blood and urine specimen are sampled both pre- and postoperatively, and several biomarkers are compared between the groups.

NCT ID: NCT02149771 Withdrawn - Clinical trials for Hepatocellular Carcinoma

Combination Treatment for Advanced Liver Cancer

Start date: May 2014
Phase: Phase 3
Study type: Interventional

The purpose of this study is to determine whether TACE combined endovascular stent implantation confers a survival benefit over TACE alone.

NCT ID: NCT02129322 Withdrawn - Clinical trials for Hepatocellular Carcinoma

Effect of Adjuvant Therapy by Sorafenib, Oxaliplatin and S-1

Start date: July 2015
Phase: Phase 2
Study type: Interventional

The study is designed to investigate the effect of adjuvant therapy by Sorafenib, Oxaliplatin and S-1 to prevent the tumor recurrence for hepatocellular carcinoma after liver transplantation

NCT ID: NCT02004210 Withdrawn - Clinical trials for Hepatocellular Carcinoma

A Phase 3 Trial Comparing TACE and TARE in Unilobar Advanced Hepatocellular Carcinoma

Start date: April 2013
Phase: Phase 3
Study type: Interventional

The aim of this study is to compare the efficacy of conventional transarterial chemoembolization(TACE) and transarterial radioembolization in patients with unilobar advanced hepatocellular carcinoma.

NCT ID: NCT01995227 Withdrawn - Clinical trials for Hepatocellular Carcinoma

An Individualized Anti-Cancer Vaccine Study in Patients With HCC

Start date: December 2013
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine the safety and the immunological, radiological, and pathological response of the personalized anti-cancer vaccine AlloVax(TM) in patients with refractory Hepatocellular Carcinoma (HCC) and who are not eligible for any approved HCC treatments or have failed all approved HCC treatments. AlloVax(TM) is a personalized anti-cancer vaccine combining Chaperone Rich Cell Lysate (CRCL) as a source of tumor antigen prepared from patient's tumor and AlloStim(TM) as an adjuvant. The combination of these two components provides a vaccine designed to bring out an immune response capable of finding and killing the tumor cells.

NCT ID: NCT01968629 Withdrawn - Clinical trials for Hepatocellular Carcinoma

24hr Imaging Of HCC After EOVIST

Start date: December 2013
Phase: Phase 0
Study type: Interventional

In this research study, the investigators are looking to see if MR imaging with Eovist performed 24 hours after the injection of Eovist helps improve the identification and characterization of focal liver tumors.