Soft Tissue Sarcoma Clinical Trial
Official title:
Alkylator-Intense Conditioning Followed by Autologous Transplantation for Patients With High Risk or Relapsed Solid or CNS Tumors
This is a standard of care treatment guideline for high risk or relapsed solid tumors or CNS tumors consisting of a busulfan, melphalan, thiotepa conditioning (for solid tumors) or carboplatin and thiotepa conditioning (for CNS tumors) followed by an autologous peripheral blood stem cell transplant. For solid tumors, if appropriate, disease specific radiation therapy at day +60. For CNS tumors, the conditioning regimen and autologous peripheral blood stem cell transplant will be given for 3 cycles.
n/a
Status | Clinical Trial | Phase | |
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Recruiting |
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A Platform of Patient Derived Xenografts (PDX) and 2D/3D Cell Cultures of Soft Tissue Sarcomas (STS)
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N/A | |
Recruiting |
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Phase 1 | |
Active, not recruiting |
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Phase 1 | |
Active, not recruiting |
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Phase 1/Phase 2 | |
Completed |
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Withdrawn |
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Phase 2 | |
Terminated |
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Phase 1 | |
Terminated |
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Safety Study of MGD009 in B7-H3-expressing Tumors
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Phase 1 | |
Completed |
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Withdrawn |
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Ferumoxytol-Enhanced MRI in Adult/Pedi Sarcomas
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N/A | |
Completed |
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Amrubicin Chemotherapy as First Line in Metastatic or Unresectable Soft Tissue Sarcoma
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Phase 2 | |
Completed |
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A Trial of TH-302 in Combination With Doxorubicin Versus Doxorubicin Alone to Treat Patients With Locally Advanced Unresectable or Metastatic Soft Tissue Sarcoma
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Phase 3 | |
Completed |
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Phase 1 | |
Recruiting |
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Phase 1/Phase 2 | |
Terminated |
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Phase 2 | |
Completed |
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Phase 1 | |
Completed |
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N/A | |
Completed |
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Recruiting |
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Terminated |
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Phase 3 |