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Hemostasis clinical trials

View clinical trials related to Hemostasis.

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NCT ID: NCT00536068 Completed - Hemostasis Clinical Trials

Platelet Inhibition by Aspirin, Acetaminophen and NSAID

Start date: August 2006
Phase: N/A
Study type: Interventional

Nonsteroidal antiinflammatory drugs such as diclofenac or naproxen may interfere with the inhibition of platelet aggregation by aspirin, because they all interact with the platelet cyclooxygenase.This may be of great clinical importance because of an increased cardiovascular event rate (myocardial infarction, stroke). The present randomized, controlled study analyses in vitro platelet aggregation under a combined treatment of healthy volunteers with aspirin and either acetaminophen, diclofenac, naproxen, or placebo.

NCT ID: NCT00469742 Completed - Clinical trials for Cardiopulmonary Bypass

Aprotinin in Neonates Undergoing Cardiopulmonary Bypass

Start date: April 2007
Phase: N/A
Study type: Observational

This is a retrospective chart review study. The purpose of this study is to review our experience at Children's Healthcare of Atlanta in neonates receiving aprotinin. We will examine the specific outcomes of renal dysfunction, thrombosis and mortality.

NCT ID: NCT00449410 Completed - Atrial Fibrillation Clinical Trials

Silent Cerebrovascular Lesion and Cognitive Decline Prevention by Cholesterol Lowering in Elderly AF Patients

SPACE
Start date: May 2005
Phase: Phase 4
Study type: Interventional

In elderly patients with atrial fibrillation (AF) the presence of silent brain infarcts and neurocognitive deficit is high despite adequate treatment with oral anticoagulation. Atherosclerosis is considered to be a chronic inflammatory disease and thrombosis and inflammation are strongly correlated. Atrial fibrillation is linked with increased levels of inflammatory markers and intensive cholesterol lowering has proven to reduce inflammation. In a prospective double-blind randomized pilot-study we want to test the hypothesis, that addition of intensive cholesterol lowering treatment besides adequate oral anticoagulation will reduce cerebrovascular lesions and will be beneficial for neurocognitive status in elderly AF patients.

NCT ID: NCT00279383 Completed - Clinical trials for Blood Loss, Surgical

OSHES - Observational Study on Hemostasis in Surgery (TC-022-IT)

Start date: August 2005
Phase: Phase 4
Study type: Observational

OSHES (= Observational Study on Hemostasis in Surgery) is a non interventional register settled in Italy with the purpose of collecting data on 800 patients intra-operatively treated with hemostatic supporting agents/techniques in addition to the standard surgical procedures in 40 surgical wards. The availability of these data will allow for a better understanding of the therapeutic needs in the area of hemostatic supporting agents/techniques.