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Hemorrhoids clinical trials

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NCT ID: NCT06459739 Completed - Anesthesia Clinical Trials

Effect of Sacral Erector Spinae Plane Block on Hemorrhoid and Pilonidal Sinus Surgery

Start date: September 1, 2023
Phase: N/A
Study type: Interventional

Introduction: This study investigated the efficacy of sacral erector spinae plane block (ESPB) for managing postoperative pain and reducing opioid consumption in patients undergoing hemorrhoid and pilonidal sinus (PS) surgery.

NCT ID: NCT06420986 Completed - Clinical trials for Hemorrhoids Third Degree

Open Hemorrohoidectomy Vs Transanal Hemorrhoidal Desarterialization in Hemorrhoids Grade III: The Effect on Symptoms

Start date: August 12, 2021
Phase: N/A
Study type: Interventional

The goal of this clinical trial is to learn if open hemorroidectomy diminishes symptoms compared to transanal hemorrhoidal desarterialization (THD) in patients presenting with hemorrhoids grade III. The main question it aims to answer is: - Do patients undergoing open hemorroidectomy present with lesser symptoms 1 year after surgery, compared to those undergoing a THD? Researchers will compare open hemorroidectomy to THD in terms of symptom response one year after the procedure. Participants will: - Undergo surgical treatment of hemorroids performed by one of the two techniques: open hemorroidectomy versus THD. - Fill in symptom forms before and one year after the surgical procedure. - Attend control visits one week, one month, three months and one year after the surgical procedure.

NCT ID: NCT06294470 Completed - Hemorrhoids Clinical Trials

Efficacy of Stapled Hemorrhoidopexy for the Treatment of Obstructive Defecation Syndrome

Start date: May 1, 2023
Phase: N/A
Study type: Interventional

The objective of this study is to assess the efficiency of the procedure for hemorrhoidal prolapse and pexia in alleviating symptoms of defecatory obstruction among patients with grade II to IV mucohemorrhoidal prolapse.

NCT ID: NCT06216223 Completed - Clinical trials for Inflammatory Bowel Diseases

Laser Versus Surgery in Anal Diseases in Inflammatory Bowel Patients

Start date: September 5, 2023
Phase: N/A
Study type: Interventional

This is a randomized comparative clinical trial carried out to compare between laser ablation and surgery in treating anal diseases in inflammatory bowel diseases patients and find out if one is superior to the other. Inflammatory bowel diseases patients with anal problems were divided into 2 groups, one group had traditional surgery and the other had laser ablation for anal diseases and results were compared between the 2 groups.

NCT ID: NCT06009133 Completed - Clinical trials for Hemorrhoids External Thrombosed

Surgical Approach for Acute External Thrombosed Hemorrhoidal Disease

Start date: July 1, 2022
Phase:
Study type: Observational

Acute external thrombosed hemorrhoidal disease (AETHH) is one of the emergent complications of hemorrhoidal disease that results in pain and loss of work force. Although surgical excision is recommended in the treatment of AETHH in the guidelines of the American Society of Colorectal Surgeons (ASCRS) and the European Society of Coloproctology (ESCP), the level of evidence is low and it is emphasized that additional studies are needed. Therefore, the investigators aimed to compare the efficacy of surgical excision with medical treatment in the treatment of AETHH.

NCT ID: NCT05984641 Completed - Hemorrhoid Pain Clinical Trials

Efficacy and Safety of CONAN® Proctological Cream for Treatment of Haemorrhoidal Disease

Start date: March 1, 2022
Phase: N/A
Study type: Interventional

Aim of the study is to assess the efficacy, safety and tolerability of CONAN® (Proctological Cream, Medical Device, Omikron Italia Srl) on most frequent symptoms in grade 1-2 of haemorrhoidal disease and anal fissures.

NCT ID: NCT05772351 Completed - Hemorrhoids Clinical Trials

Preoperative Micronized Flavonoid Fraction (MFF) Use in Multimodal Anesthesia in Anorectal Surgery

Start date: November 25, 2021
Phase: N/A
Study type: Interventional

Aim: To assess the efficiency of the micro-flavonoid fraction (MMF) administration prior to anorectal surgery with spinal anesthesia on postoperative pain severity reduction. Methods: Patients who meet the following criteria are included: participants must be diagnosed with surgical treatment of anorectal diseases. All participants are randomly divided into 2 groups: the first one gets a tablet with 1000 mg MFF (Detralex®), the second one gets a tablet containing starch per os 14 days before surgery (72 participants per arm). Then patients of each group will continue MFF administration for 30 days after surgery. Patients of both arms receive spinal anesthesia and undergo surgery. Following the procedure the primary and secondary outcomes are evaluated: frequency of the opioid drugs intake, the severity of the postoperative pain syndrome, duration and frequency of other drugs intake, readmission rate, overall quality of life, time from the procedure to returning to work and the complications rate, C-reactive protein level. Discussion: the MFF intake allows reducing the severity of the hemorrhoidal disease symptoms during conservative treatment. In addition, the Detralex® efficacy has been proven in postoperative pain reduction for patients diagnosed with varicose veins of the lower extremities. The investigators intend to evaluate the feasibility of the preoperative MFF administration for the postoperative pain reduction and the decrease of the postoperative complications in patients with hemorrhoidal disease.

NCT ID: NCT05605080 Completed - Hemorrhoids Clinical Trials

Hemostatic and Analgesic Effect of Gel Foam and Gauze With Bosmin After Anal Surgery

Start date: November 7, 2022
Phase: N/A
Study type: Interventional

To evaluate the hemostatic and analgesic effect of using gauze with Bosmin or Gelfoam after anal surgery.

NCT ID: NCT05602987 Completed - Hemorrhoids Clinical Trials

Comparison Study of the Effect of Enema in Anal Surgery

Start date: November 14, 2022
Phase: N/A
Study type: Interventional

To evaluate whether receiving enema before anal surgery or not affects the postoperative recovery and complications.

NCT ID: NCT05348200 Completed - Hemorrhoids Clinical Trials

Safety and Efficacy of CITI-002 in Adult Patients With Moderate Grade Hemorrhoids

Start date: April 22, 2022
Phase: Phase 2
Study type: Interventional

A Randomized Phase 2 double blind study which aims to determine the safety and efficacy of CITI-002 cream in adult patients with Goligher's grade II or III hemorrhoids.