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Hemorrhage clinical trials

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NCT ID: NCT03267446 Recruiting - Clinical trials for Antepartum Hemorrhage

Doppler Imaging and Morbidly Adherent Placenta

Start date: August 29, 2017
Phase: N/A
Study type: Interventional

The aim of this study is to assess the value of adding 3D power Doppler (as a diagnostic technique) to gray scale technique in the antenatal diagnosis of morbidly adherent placenta as well as predict the surgical outcome regarding the type of surgery and the intra operative morbidities.

NCT ID: NCT03264781 Recruiting - Uterine Bleeding Clinical Trials

The Effect of Cyclofem® for the Treatment of Irregular Uterine Bleeding in Implant Contraceptive Users

Start date: August 2016
Phase: Phase 1/Phase 2
Study type: Interventional

The purpose of this study is to determine that once-a-month injectable contraceptive( Cyclofem® ) has the effect on treatment of irregular uterine bleeding in implant contraceptive users or not.

NCT ID: NCT03260153 Recruiting - Clinical trials for Intracerebral Hemorrhage

Deproteinised Calf Blood Serum Injection for the Treatment of Acute Intracerebral Hemorrhage

Start date: January 2017
Phase: N/A
Study type: Interventional

The purpose of this study is to investigate the efficacy and safety of Deproteinised Calf Blood Serum Injection in alleviating perihematomal edema (PHE) and secondary brain injury, as well as neurologic deficits in patients with acute intracerebral hemorrhage (ICH).

NCT ID: NCT03255174 Recruiting - Clinical trials for Controlling Mild to Moderate Bleeding During Surgery

The EVARREST® Pediatric Mild or Moderate Liver and Soft Tissue Bleeding Study

Start date: March 20, 2018
Phase: Phase 3
Study type: Interventional

The objective of this study is to evaluate the safety and hemostatic effectiveness of EVARREST as an adjunct to controlling mild to moderate soft hepatic parenchyma or soft tissue bleeding during open hepatic, abdominal, pelvic, retroperitoneal, and thoracic (non-cardiac) surgery in pediatric population.

NCT ID: NCT03253263 Recruiting - Clinical trials for Bronchopulmonary Dysplasia

A Clinical Efficacy and Safety Study of OHB-607 in Preventing Bronchopulmonary Dysplasia in Extremely Premature Infants

Start date: May 9, 2019
Phase: Phase 2
Study type: Interventional

The purpose of this study is to determine if an investigational drug can prevent Bronchopulmonary Dysplasia, reducing the burden of chronic lung disease in extremely premature infants, as compared to extremely premature infants receiving standard neonatal care alone.

NCT ID: NCT03251469 Recruiting - Hip Fractures Clinical Trials

Single Dose of Tranexamic Acid and Blood Loss, in Elderly Patients With Hip Fracture

Start date: January 2013
Phase: Phase 2
Study type: Interventional

The aim of this study is to investigate the hypothesis that single dose of tranexamic acid (TXA) preoperatively will lower blood loss and transfusion rate in elderly patients with hip fractures (intertrochanteric or Subcapital), that will be treated with intramedullary nailing and cemented hemiarthroplasty respectively. After application of inclusion and exclusion criteria, patients will be randomized in two groups. Group 1 will include patients that receive preoperatively single dose of TXA (15mg/kg) and Group 2 will include patients that receive normal saline (control group).

NCT ID: NCT03245866 Recruiting - Clinical trials for Subarachnoid Hemorrhage

Swiss Study on Subarachnoid Hemorrhage

Swiss-SOS
Start date: January 1, 2009
Phase:
Study type: Observational [Patient Registry]

This registry was created to assess management parameters of patients treated for aneurysmal subarachnoid hemorrhage in Switzerland. All Swiss hospitals with a neurosurgery department, an intensive care unit and an interventional neuroradiology team that treat neurovascular emergencies participate in the registry. Clinical parameters are entered into a common database. This database will provide (1) a nationwide assessment of the current standard of care and (2) the outcomes for patients in Switzerland including neuropsychological assessments.

NCT ID: NCT03243175 Recruiting - Atrial Fibrillation Clinical Trials

Avoiding Anticoagulation After IntraCerebral Haemorrhage

A3ICH
Start date: January 24, 2019
Phase: Phase 3
Study type: Interventional

Randomised controlled trials (RCTs) demonstrate a substantial benefit from oral anticoagulant drugs for the prevention of stroke and systemic embolism in non-valvular atrial fibrillation (AF). However, these RCTs excluded patients with prior intracerebral haemorrhage (ICH). Therefore, guidelines are unable to recommend whether oral anticoagulant drugs, in particular non-vitamin K antagonist (called direct OAC) - can be used for patients with AF after an intracerebral haemorrhage. Roughly 30% of adults with ICH have AF but in 2017 it remains unclear whether they should start oral anticoagulant drugs, be treated with left atrial appendage closure (LAAC) or avoid anticoagulation and LAAC.

NCT ID: NCT03212872 Recruiting - Clinical trials for Chronic Liver Disease

Blood Ammonia as Predictor for Esophageal Varices and Risk of Bleeding

EV
Start date: July 7, 2016
Phase: N/A
Study type: Interventional

Assessment of blood ammonia level as a non-invasive predictor for presence of EV and risk of bleeding

NCT ID: NCT03201094 Recruiting - Inflammation Clinical Trials

Impact of NMES and HPRO on Recovery After SAH- Pilot Study

Start date: December 1, 2017
Phase: N/A
Study type: Interventional

The study purpose is to investigate the hypothesis that in adults with SAH, early neuromuscular electrical stimulation (NMES) and high protein supplementation (HPRO) will improve muscle mass, metabolic and inflammatory biomarker profiles, compared to SAH controls receiving standard of care interventions for nutrition and mobilization. The investigators will accomplish this by studying the effects of a high protein (HPRO) nutritional treatment as well as NMES intervention have upon muscle wasting and motor strength acutely after SAH. This will be addressed in a prospective trial of SAH patients receiving HRPO with NMES as compared to age and severity-matched SAH patients undergoing standard of care interventions for nutrition and mobilization. Additionally, the study will investigate the impact HPRO and NMES interventions have upon inflammatory cytokines and markers of energy balance. Results of this study will establish evidence for precision nutrition plus early exercise to mitigate the catabolic and inflammatory state produced by SAH to improve muscle, metabolic, and health recovery outcomes.