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Hemodialysis clinical trials

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NCT ID: NCT00749619 Completed - Clinical trials for End Stage Renal Disease

Addition of Heparin to Taurolock-TM CLS in HD Patients With TCC Dose it Improve Catheter Patency Problems ?

Start date: May 2007
Phase: Phase 3
Study type: Interventional

Addition of Heparin to the Catheter Lock Solution (CLS): Taurolock-TM will improve the vascular patency compared to Taurolock-TM alone , in hemodialysis patients with Tunneled Cuffed Catheter(TCC) as vascular access.

NCT ID: NCT00744445 Completed - Anemia Clinical Trials

Erythropoietin Therapy in Patients With Chronic Renal Failure: A Study of Time Dependent Activity

Start date: October 1993
Phase: Phase 2
Study type: Interventional

The purpose of this research study was to determine if the activity of erythropoietin (r-HuEPO) is time dependent when given to chronic renal failure patients at three different times of day.

NCT ID: NCT00737672 Completed - Hemodialysis Clinical Trials

GORE VIABAHN Endoprosthesis Versus Percutaneous Transluminal Angioplasty (PTA) to Revise AV Grafts in Hemodialysis

REVISE
Start date: September 2008
Phase: Phase 3
Study type: Interventional

The objective of the study is to establish efficacy and safety of the GORE VIABAHN® Endoprosthesis with PROPATEN Bioactive Surface when used to revise arteriovenous (AV) prosthetic grafts at the venous anastomosis in the maintenance or re-establishment of vascular access for hemodialysis.

NCT ID: NCT00727519 Completed - Clinical trials for End Stage Renal Disease

The Effect of Pomegranate Juice on Oxidative Stress in Hemodialysis Patients

Start date: July 2008
Phase: Phase 3
Study type: Interventional

Pomegranate juice (PJ) consumption by hemodialysis patients will reduce the oxidative stress and the incidence of infections, cardiovascular events and mortality.

NCT ID: NCT00724633 Completed - Hemodialysis Clinical Trials

Effect of Lowering the Dialysate Sodium on Blood Pressure in Hemodialysis Patients

Start date: November 1, 2011
Phase: Phase 3
Study type: Interventional

Patients currently receiving hemodialysis will be randomized to receive 1 of 3 dialysate sodium prescriptions. The effects on blood pressure, interdialytic weight gain, thirst, and intradialytic symptoms will be assessed.

NCT ID: NCT00701805 Completed - Hemodialysis Clinical Trials

Long-term Safety Study of Paricalcitol Injection in Chronic Kidney Disease Patients With Hemodialysis (HD)

Start date: July 2008
Phase: Phase 2
Study type: Interventional

The purpose of this study is to evaluate the long-term safety of paricalcitol injection. Subjects will administer clinical supplies 3 times a week, 40 weeks at dialysis session in dose-titration manner, following 12 weeks of treatment in the dose-response study, M10-309 (NCT00667576).

NCT ID: NCT00694031 Completed - Hemodialysis Clinical Trials

Survival Study in Patients Undergoing On-line Hemodiafiltration

ESHOL
Start date: May 2007
Phase: Phase 4
Study type: Interventional

Patients on hemodialysis will be randomly assigned (1:1) to continue on conventional hemodialysis or on-line hemodiafiltration, both three times per week. A 3 year follow-up and a sample size of around 750 will be necessary to detect a 35% reduction in mortality.

NCT ID: NCT00686751 Completed - Clinical trials for Cardiovascular Disease

Immune Effects of Vitamin D in Hemodialysis Patients

Start date: December 2004
Phase: Phase 2
Study type: Interventional

The purpose of this study to examine whether vitamin D can reduce the activation of the immune system during dialysis. When activated, the immune cells release certain substances, called cytokines, which can be measured from small blood samples. We want to study to what degree the immune system is activated during a regular dialysis treatment and whether the time point of vitamin D administration, either right before the start or right at the end of a dialysis treatment, has an impact on the activation of the immune system.

NCT ID: NCT00663403 Completed - Hemodialysis Clinical Trials

Pharmacokinetics of Daptomycin in Critically Ill Patients Receiving Continuous Venovenous Hemodialysis (CVVHD)

Start date: February 2007
Phase: Phase 4
Study type: Interventional

Daptomycin is an antibiotic that is affective against many strains of antibiotic resistant microorganisms. This antibiotic would be appropriate for use in the intensive care unit (ICU) considering the severity of illness and high risk for infection within this hospital environment. While in the ICU, patients may develop acute renal failure. Approximately 75% of ICU patients who develop acute renal failure will require some form of renal replacement therapy until their kidneys recover. Continuous hemodialysis is becoming one of the most common forms of dialysis in the ICU as it is a gentle type of dialysis provided over longer periods of time. The current data demonstrating the ability of continuous hemodialysis to remove daptomycin from the body is derived from in-vitro trials. The purpose of this trial is to determine the extent of daptomycin removal from critically ill patients receiving continuous hemodialysis. Findings from this trial will be used to develop new dosing recommendations for daptomycin in continuous hemodialysis.

NCT ID: NCT00654017 Completed - Hemodialysis Clinical Trials

A Study Evaluating the Efficacy and Safety of Sildenafil in Patients With Erectile Dysfunction Receiving Hemodialysis

Start date: October 2002
Phase: Phase 4
Study type: Interventional

The study was done to evaluate the efficacy, safety, and tolerability of orally administered sildenafil taken as needed about one hour before sexual activity after a 10-week period in male outpatients with erectile dysfunction and severe renal failure who were on hemodialysis.