Clinical Trials Logo

Clinical Trial Summary

This study is a multi-center, longitudinal cohort study of 125 infants with craniofacial microsomia (CFM) and 100 infants without craniofacial anomalies. Participants will undergo a series of evaluations between 0-3 years of age to comprehensively evaluate the developmental status of infants and toddlers with CFM. This research design will also explore specific pathways by which CFM may lead to certain outcomes. Specifically, the study explores (1) the longitudinal relations between facial asymmetry and emotion-related facial movements and socialization; and (2) associations among ear malformations, hearing and speech deficits and cognitive outcomes. Results of this research will ultimately lead to future investigations that assess new interventions and corresponding changes in current standards of care for children with CFM.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms


NCT number NCT02224677
Study type Observational
Source Seattle Children's Hospital
Contact
Status Completed
Phase
Start date November 2013
Completion date August 31, 2019

See also
  Status Clinical Trial Phase
Recruiting NCT05288790 - Microbiome Metabolites and Alcohol in HIV to Reduce CVD RCT Phase 2
Recruiting NCT05963659 - Nitrate Modulates Cognitive Impairment Via Oral Microbiota. N/A
Completed NCT04130321 - Demonstration of the Prebiotic-like Effects of Camu-camu Consumption Against Obesity-related Disorders in Humans N/A
Recruiting NCT05929976 - InterNatIonal CHildhood Leukemia Microbiome/MEtabolome Cohort
Withdrawn NCT04230746 - Effect of Antibiotics on Urinary Microbiome Early Phase 1
Active, not recruiting NCT06289283 - Microbiota in Urine and Urothelium Can be a Factor for Induction of Urinary Bladder Cancer. The Study Will Examine Urine and Bladder Cancer Tissues From Male Patients and Urine of Controls Using Whole Genomic Sequencing Techniques and 16S rRNA. The Aim is to Elucidate Role of Microbiota in Bladder
Recruiting NCT05714566 - Research on Gut Microbiome and Metabolomics Alterations in C.Difficile Infected IBD Patients
Enrolling by invitation NCT06225336 - Subcutaneous Implant Combination Product (AUR-201) in Patients With Unilateral Microtia (Australia) Phase 1
Recruiting NCT05068362 - Auricular Reconstruction in Microtia by Medpor Implant Following Tissue Expansion N/A
Not yet recruiting NCT05615116 - Clinical Study on the Distribution of Digestive Tract Microbiota Before and After Ileocecal Resection in Crohn's Disease
Enrolling by invitation NCT06220994 - the Gut Microbiome and Metabolomics in Chronic Lower extreMities Threatening Ischemia
Completed NCT00958802 - Tissue Engineering Microtia Auricular Reconstruction: in Vitro and in Vivo Studies Phase 0
Recruiting NCT06087874 - Preventive Effect of Perinatal Oral Probiotic Supplementation (POPS) on Neonatal Jaundice Phase 2
Suspended NCT03624608 - Evaluation of the Auryzon Devices in the Optimization of Ear and Nose Reconstruction Procedures N/A
Not yet recruiting NCT06394687 - The Digestion of Protein Powders in Healthy Participants Using SIMBA and LIMBA Capsule N/A
Completed NCT05417360 - Akkermansia and Weight Maintenance N/A
Recruiting NCT02518035 - Silicone Gel to Improve Scar in Microtia Patients Phase 4
Recruiting NCT06078566 - Long-Term Follow-Up Study of Unilateral Microtia Patients Implanted With AUR-201 Phase 1/Phase 2
Recruiting NCT06072040 - Subcutaneous Implant Combination Product (AUR-201) in Patients With Unilateral Microtia Phase 1/Phase 2
Not yet recruiting NCT03729427 - Rib Microtia and the Erector Spinae Plane (ESP) Block N/A