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Research on Gut Microbiome and Metabolomics Alterations in C.Difficile Infected IBD Patients

Inflammatory Bowel Diseases Clinical Trial

Official title:
Research on Biomarkers of Clostridioides Difficile Infection in Inflammatory Bowel Disease Patients Defined by Gut Microbiome and Fecal Metabolomics Alterations

Clinical Trial Summary

The goal of this research is to compare alterations of gut microbiota and fecal metabolomics alterations between inflammatory bowel disease patients infected with or without Clostridioides difficile. The main questions it aim to answer are: which bacterial genus or fecal metabolites can discriminate IBD patients infected or more likely to be infected with Clostridioides difficile and their role in the pathogenesis of Clostridioides difficile. type of study: observational study participant population/health conditions 1. population diagnosed with Ulcerative colitis or Crohn's disease 2. Having diarrhea Participants will be included in this research. If there is a comparison group: Researchers will compare healthy people without IBD or any diarrhea to see if disease or diarrhea would affect the gut microbiota and metabolites.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05714566
Study type Observational [Patient Registry]
Source RenJi Hospital
Contact Yang
Phone 13262906006
Email 15828660135@163.com
Status Recruiting
Phase
Start date November 7, 2022
Completion date December 30, 2024
View Details
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