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A Long-term Follow-up Study of Subjects Who Received CRISPR CAR T Cellular Therapies

Hematologic Malignancy Clinical Trial

Official title:
A Long-term Follow-up Study of Subjects With Malignancies Treated With CRISPR CAR T Cellular Therapies

Clinical Trial Summary

This study will evaluate the long-term safety and efficacy of CRISPR CAR T cellular therapies

Clinical Trial Description

All subjects with hematological and solid malignancies who are enrolled in a parent study and were exposed to allogeneic CRISPR CAR T cellular therapy will be asked to participate in this long-term follow-up (LTFU) study. Subjects who have completed the parent study for the protocol-defined duration, or who have discontinued the parent study early, or who are in secondary follow-up (follow up of subjects with progressive disease or who receive a subsequent line of anticancer therapy) in the parent study may enroll in this LTFU study. This will allow for collection of long-term efficacy data (as applicable) and safety data up to 15 years post-treatment with CRISPR CAR T cellular therapies. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06208878
Study type Observational
Source CRISPR Therapeutics
Contact
Status Enrolling by invitation
Phase
Start date November 22, 2023
Completion date August 2038
View Details
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