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Acquiring and Targeting Heat Exposures Necessary for Action — ATHENA  

Heat Stress Clinical Trial

Official title:
Enhancing Lethality by Targeting Cognitive and Physiological Mechanisms of Female Warfighter Resiliency to Consecutive Days of Intense Exercise in the Heat

Clinical Trial Summary

The purpose of this research study is to better understand ways that women and men differ physiologically, cognitively, physically, and cellularly to better prescribe helpful interventions that will prevent injury and risk of conditions like exertional heat illnesses or heatstroke. The main questions this project aims to answer are: 1. What is the relative stress contributing to performance differences between women and men during intense exercise in extremely hot and humid environments in response to exertional heat stress? 2. What is the relative contribution of responses in adipose tissue, cardiovascular tissue, gut microbiota, and musculoskeletal tissue on heat tolerance in women (vs. men) to exertional heat stress? 3. What is the impact of adding an antioxidant juice consumption regime and will it assist in enhancing performance during an acute bout of exercise-heat stress before and after heat acclimation? Subjects enrolled and approved for participation will perform: 1. a heat acclimation protocol which includes the completion of 5 days of prescribed exercise-heat exposure 2. two separate acute exercise-heat exposures for the assessment of thermotolerance and the investigation of potential enhancements in thermoregulatory performance that may occur after the completion of a 5-day heat acclimation protocol 3. a subset of subjects enrolled and approved for participation who opt in to antioxidant berry supplement consumption will either consume the active or placebo product throughout their participation.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05678738
Study type Interventional
Source University of Connecticut
Contact Elaine C Lee, PhD
Phone 860-486-3169
Email elaine.c.lee@uconn.edu
Status Recruiting
Phase N/A
Start date September 16, 2021
Completion date October 31, 2024
View Details
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