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Clinical Trial Summary

The primary purpose of the study was to describe the tolerability of treatment with the optimal dose of LCZ696 (97 mg sacubitril / 103 mg valsartan bid), over six (6) months, in patients with heart failure with reduced ejection fraction (HFrEF) in Canada.

The study was also to describe the overall tolerability, effectiveness and safety of LCZ696 for the management of HFrEF over 12 months of treatment, as well as describe the patterns of LCZ696 up and down dose titrations occurring during the management of patients with HFrEF.


Clinical Trial Description

n/a


Study Design


Related Conditions & MeSH terms

  • Heart Failure
  • Hearth Failure With Reduced Ejection Fraction (HFrEF)

NCT number NCT02690974
Study type Interventional
Source Novartis
Contact
Status Completed
Phase Phase 4
Start date March 8, 2016
Completion date November 29, 2017