Heart Failure With Improved Ejection Fraction and Deep Learning

Heart Failure Clinical Trial

Official title:

Deep Learning-Based Prediction Model of Heart Failure With Improved Ejection Fraction

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT06070506
• Other study ID #: 2020020668
• Status: Completed
• Start date: March 1, 2022
• Est. completion date: May 20, 2023

Study information

• Verified date: October 2023
• Source: First Affiliated Hospital of Harbin Medical University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The aim of this study was to design a deep learning-based trained model to assist in HFimpEF diagnosis.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 422
• Est. completion date: May 20, 2023
• Est. primary completion date: December 31, 2022
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

1. Age >18 years.

2. The diagnostic criteria of HF follows the 2018 Chinese Guidelines for the Diagnosis and Treatment of Heart Failure, having symptoms of dyspnea, fatigue or decreased activity tolerance, having signs of fluid retention (such as pulmonary congestion and peripheral edema), having echocardiogram abnormalities in cardiac structure and/or function, showing elevated natriuretic peptide levels (BNP>35 ng/L or/and N-terminal pro-BNP >125 ng/L).

3. Have reviewing echocardiography after discharge.

Exclusion Criteria:

1. Patients with hypertrophic, restrictive, or invasive cardiomyopathy and congenital or rheumatic heart disease.

2. Patients with heart transplantation during follow-up.

Related Conditions & MeSH terms

• Diagnosis
• Heart Failure

Locations

Country	Name	City	State
China	Yihui Kong	Harbin	Heilongjiang

Sponsors (1)

Lead Sponsor	Collaborator
Yihui Kong

Country where clinical trial is conducted

China, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	change of left ventricular ejection fraction	left ventricular ejection fraction value in millimeters	3 months
Secondary	change of clinical predictor of EF improvement	weight in kilograms, height in meters(weight and height will be combined to report BMI in kg/m^2)	3 months
Secondary	the independent clinical predictor of HFimpEF	prealbumin in mg/L	3 months