Cardiovascular Assessment of Pediatric Cancer Survivors

Heart Failure Clinical Trial

— CASPER  

Official title:

Cardiovascular Assessment of Pediatric Cancer Survivors: Understanding Long-Term Effects and Risks

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT05939089
• Other study ID #: COEXIST-2
• Status: Completed
• Start date: January 1, 2023
• Est. completion date: June 22, 2023

Study information

• Verified date: July 2023
• Source: Istanbul University
• Contact: n/a
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

The goal of this observational study is to evaluate cardiac and vascular health status of pediatric cancer survivors.

Description:

All pediatric cancer survivors were evaluated with cardiological examination, ECG, transthoracic echocardiography (transesophageal echocardiography when required), NT-proBNP, cTnI, kidney function tests, liver function tests, fasting blood glucose, cholesterol panel, iron, iron binding capacity, ferritin, transferrin saturation, B12, vitamin D, folic acid, urinanalysis, hemogram and a questionnaire about living with heart failure.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 54
• Est. completion date: June 22, 2023
• Est. primary completion date: June 15, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Diagnosed cancer at pediatric age

Exclusion Criteria:

• Having cancer after 18 years of age

Related Conditions & MeSH terms

• Heart Failure
• Left Ventricular Dysfunction
• Ventricular Dysfunction
• Ventricular Dysfunction, Left

Intervention

Diagnostic Test:
• ECG, Echocardiography, cTnI, NT-ProBNP
All pediatric cancer survivors are evaluated with cardiological examination, ECG, transthoracic echocardiography (transesophageal echocardiography when required), NT-proBNP, cTnI, kidney function tests, liver function tests, fasting blood glucose, cholesterol panel, iron, iron binding capacity, ferritin, transferrin saturation, B12, vitamin D, folic acid, urinanalysis, hemogram and a questionnaire about living with heart failure.

Locations

Country	Name	City	State
Turkey	Istanbul Faculty of Medicine	Fatih	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Istanbul University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Rate of LV Dysfunction	Echocardiographic evaluation of left ventricular functions	From the first visit at cardio-oncology division through study completion, an average of 2 years