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Aerobic Versus Combined Exercise and Diastolic Dysfunction

Heart Failure Clinical Trial

Official title:
Effects of Exercise Training on Diastolic and Systolic Dysfunction in Patients With Chronic Heart Failure

Clinical Trial Summary

Thirty-two stable patients with chronic heart failure participated in an exercise rehabilitation program. They randomly assigned to aerobic exercise (AER) or combined aerobic and strength training (COM). Before and after the program, they underwent a symptom-limited maximal cardiopulmonary exercise testing and serial echocardiography evaluation examining the indices of diastolic dysfunction (DD).

Clinical Trial Description

Thirty-two stable patients with chronic heart failure (age: 56 ± 10 years, EF: 32 ± 8%, 88 % men) participated in an exercise rehabilitation program. They randomly assigned to aerobic exercise (AER) or combined aerobic and strength training (COM), based on age and peak oxygen uptake, as stratified randomization criteria. Before and after the program, they underwent a symptom-limited maximal cardiopulmonary exercise testing (CPET) and serial echocardiography assessment to evaluate peak oxygen uptake (VO2peak), peak workload (Wpeak), DD grade, right ventricular systolic pressure (RVSP) and EF. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04916184
Study type Interventional
Source Evangelismos Hospital
Contact
Status Completed
Phase N/A
Start date January 1, 2016
Completion date February 1, 2021
View Details
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