Impact of Additional Resistance Training During Rehabilitation Therapy in Patients With Heart Failure

Heart Failure Clinical Trial

Official title:

Impact of Different Types of Resistance Training Additional to Endurance Training During Rehabilitation Therapy in Patients With Heart Failure

Clinical Trial Details — Status: Not yet recruiting

Administrative data

• NCT number: NCT04688827
• Other study ID #: 2020044
• Status: Not yet recruiting
• Phase: N/A
• Start date: August 1, 2021
• Est. completion date: January 1, 2023

Study information

• Verified date: July 2021
• Source: Hasselt University
• Contact: Dominique Hansen, Professor
• Phone: 011 29 21 26
• Email: dominique.hansen[@]uhasselt.be
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The impact of moderate- or low-intensity resistance training will be investigated additional to endurance training in heart failure patients following rehabilitation. The aim is to optimize intensity of resistance training in this patient population.

Recruitment information / eligibility

• Status: Not yet recruiting
• Enrollment: 30
• Est. completion date: January 1, 2023
• Est. primary completion date: January 1, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Diagnosis of heart failure and participation in cardiac rehabilitation

Exclusion Criteria:

• Orthopedic disorders, neurological disorders affecting muscle strength, cognitive disorders, heart or arterial surgery (percutaneous coronary intervention, bypass, heart valve surgery) in the last year, acute myocardial infarction in the last 6 months, participation in another intervention

Related Conditions & MeSH terms

• Heart Failure

Intervention

Other:
• Exercise therapy
15 weeks of resistance training (additional to endurance training)

Locations

Country	Name	City	State
Belgium	Ziekenhuis Oost-Limburg	Genk	Limburg

Sponsors (2)

Lead Sponsor	Collaborator
Hasselt University	Ziekenhuis Oost-Limburg

Country where clinical trial is conducted

Belgium, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	VO2peak	Maximal oxygen consumption during cardiopulmonary exercise test	Prior to the intervention
Primary	VO2peak	Maximal oxygen consumption during cardiopulmonary exercise test	After 15 weeks of intervention
Primary	VO2peak	Maximal oxygen consumption during cardiopulmonary exercise test	After 24 weeks of follow-up
Secondary	Muscle strength	One-repetition maximum test (1RM) to evaluate maximal contraction of the muscle	Prior to the intervention
Secondary	Muscle strength	One-repetition maximum test (1RM) to evaluate maximal contraction of the muscle	After 15 weeks of intervention
Secondary	Muscle strength	One-repetition maximum test (1RM) to evaluate maximal contraction of the muscle	After 24 weeks of follow-up
Secondary	Functional capacity	Functional capacity evaluated via the six-minute walking test	Prior to the intervention
Secondary	Functional capacity	Functional capacity evaluated via the six-minute walking test	After 15 weeks of intervention
Secondary	Functional capacity	Functional capacity evaluated via the six-minute walking test	After 24 weeks of follow-up
Secondary	Quality of life in heart failure patients	Evaluation via Minnesota living with heart failure questionnaire	Prior to the intervention
Secondary	Quality of life in heart failure patients	Evaluation via Minnesota living with heart failure questionnaire	After 15 weeks of intervention
Secondary	Quality of life in heart failure patients	Evaluation via Minnesota living with heart failure questionnaire	After 24 weeks of follow-up
Secondary	Cardiac function	left-ventricular ejection fraction evaluated by transthoracic echocardiography	Prior to the intervention
Secondary	Cardiac function	left-ventricular ejection fraction evaluated by transthoracic echocardiography	After 15 weeks of intervention
Secondary	Cardiac function	left-ventricular ejection fraction evaluated by transthoracic echocardiography	After 24 weeks of follow-up
Secondary	Anthropometric measurements	body weight evaluated to determine body mass index	Prior to the intervention
Secondary	Anthropometric measurements	body weight evaluated to determine body mass index	After 15 weeks of intervention
Secondary	Anthropometric measurements	body weight evaluated to determine body mass index	After 24 weeks of follow-up