Relationships and Differences Analysis in Heart Failure

Heart Failure Clinical Trial

— REDEAL-HF  

Official title:

Retrospektive Datenanalyse Von Herzinsuffizienzpatienten in Der Kardiologie Des Universitätsklinikums Würzburg

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT03966729
• Other study ID #: REDEAL-HF
• Status: Recruiting
• Start date: January 1, 2009
• Est. completion date: December 31, 2023

Study information

• Verified date: July 2022
• Source: Wuerzburg University Hospital
• Contact: Peter Nordbeck, MD, PhD
• Phone: +49 931 201 39181
• Email: nordbeck_p[@]ukw.de
• Is FDA regulated: No
• Study type: Observational

Clinical Trial Summary

This study characterizes heart failure patients who attended the University Hospital Würzburg. The primary aim is a better understanding of the relationships and differences between the subgroups HFrEF (EF < 40%), HFmrEF (EF 40-49%), and HFpEF (EF>50%), contributing to an improved diagnosis, prognosis and therapy of patients with heart failure.

Description:

The varying clinical picture of heart failure (HF) represents a major challenge for patient care in Germany. HF is one of the most common reasons for hospitalization in the Western world. In the chronic course of heart failure, affected patients are committed to morbidity, lifelong therapy and high risk of cardiac decompensation, also associated with high mortality. Heart failure patients, who visited the Cardiology Department of the University Hospital Wuerzburg, shall be analyzed with regard to all clinical data and outcome. This retrospective work should help to better understand the three groups HFrEF (EF < 40%), HFmrEF (EF 40-49%) and HFpEF (EF>50%) and help identifying similarities and differences between the groups. Hereby we hope for progress in diagnostic, prognostic and therapeutic aspects of heart failure.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 3000
• Est. completion date: December 31, 2023
• Est. primary completion date: December 31, 2023
• Accepts healthy volunteers: No
• Gender: All
• Age group: 18 Years and older

Eligibility

Inclusion Criteria:

• Diagnosis: Heart failure
• Minimum of two echocardiographic examinations in a minimum time frame of six months
• Patients must have reached the age of 18

Related Conditions & MeSH terms

• Chronic Heart Disease
• Chronic Heart Failure
• Heart Diseases
• Heart Failure

Intervention

Other:
• Time (outcome)

Locations

Country	Name	City	State
Germany	University Hospital Würzburg	Würzburg	Bavaria

Sponsors (1)

Lead Sponsor	Collaborator
Wuerzburg University Hospital

Country where clinical trial is conducted

Germany, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Long-term survival in heart failure patients with preserved, mid-range or reduced left ventricular ejection fraction	Survival of patients with heart failure extracted from medical record or by telephone interview	1 year follow up after last examination
Secondary	Impact of clinical imaging and laboratory parameters on long-term survival in heart failure patients with precerved, mid-range or reduced left ventricular ejection fraction	Parameters are derived from standard echocardiography, cardiac magnetic resonance imaging and blood testing.	6 months