Heart Failure Clinical Trial
Official title:
Impact of Advance Care Planning on Care for Patients With Advanced Heart Failure: A Randomized Controlled Trial
Aims: Advance care planning (ACP) is considered to be one of the most promising interventions
to enable patients with life limiting illnesses to receive treatment at the end of life (EOL)
according to their own preferences and to promote EOL conversations between patients and
their health care providers. Through a 2-arm randomized controlled trial (RCT) of patients
with Class III and IV heart failure (New York Heart Association Functional Classification),
we propose to assess:
1. Whether patients in the ACP arm have a greater likelihood of receiving EOL care
consistent with their preferences as stated in the latter of the last ACP document or
the last patient interview, compared to patients in the control arm.
2. Heath care costs during study duration between patients in ACP and control arms.
3. Patient's understanding of own illness and their participation in decision making
between the ACP and control arms.
4. Patient's quality of life, anxiety and depression between ACP and control arms.
Methodology: A total of 254 patients with advance heart failure will be randomized to receive
intervention (ACP arm; N=127) or usual care (control arm; N=127).
The RCT will be conducted at the National Heart Centre and Singapore General Hospital.
Patients in both arms will be followed for one year or till death, whichever is earlier, and
interviewed every 4 months during this duration.
Clinical Significance: If benefits of ACP are shown to add value through this trial, then
this study will help to promote acceptance of ACP among patients and health care providers
across Singapore and elsewhere.
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