Heart Failure Clinical Trial
Official title:
Non-invasive Assessment of Liver Stiffness/Fibrosis by Transient Elastography (Fibroscan) in Patients With Left and/or Right Sided Heart Failure
This study will involve 70 patients who attend the Alfred Hospital with acute or chronic
heart failure as well as 30 age and gender matched control subjects. All participants will
have their history taking and a physical examination to detect symptoms and signs of heart
failure.
The main objectives are for determining the benefit and usefulness of Fibroscan (Liver scan)
in detecting liver stiffness (a condition caused by excess fluid build up in the liver which
has a negative impact on the livers ability to function properly) in heart failure patients
and for characterizing the incidence and severity of liver stiffness in this group of
patients.
After informed consent, a blood sample will be taken from all patients to assess their full
blood examination, glucose, lipid profiles, renal function and so on.
Then 24-48 hours after enrollment, the liver doctors will do the liver scan (Fibroscan) by
transient elastography. All the data are recorded and further analysis will be assessed.
In a small group of acute patients the blood tests and liver scan will be repeated just
prior to their discharge.
Optional Sub-study: For participants who consent to the optional sub-study another 20 ml of
blood for serum liver fibrotic markers will be collected.
n/a
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