Heart Failure Clinical Trial
— BACHOfficial title:
Biomarkers in Acute Heart Failure: An International, Multi-Center Trial Evaluating the Prognostic and Diagnostic Utility of Biomarkers in Patients With Heart Failure Presenting With Shortness of Breath
Verified date | July 2008 |
Source | Brahms AG |
Contact | n/a |
Is FDA regulated | No |
Health authority | United States: Institutional Review Board |
Study type | Observational |
Primary Objectives
1. Mid Region pro Adrenomedullin (MR-proADM) is superior to BNP for the prognosis of heart
failure (HF) patients and adds incremental value in predicting outcomes for patients
presenting to the Emergency Department (ED) with shortness of breath.
2. Mid Region pro A-Type Natriuretic Peptide (MR-proANP) is non-inferior to BNP for the
diagnosis of HF in patients presenting to the ED with shortness of breath.
Status | Completed |
Enrollment | 1641 |
Est. completion date | June 2008 |
Est. primary completion date | May 2008 |
Accepts healthy volunteers | No |
Gender | Both |
Age group | 18 Years and older |
Eligibility |
Inclusion Criteria: - Eighteen years of age or older. - The patients must be seen in the urgent care or emergency area with a chief complaint of shortness of breath not due to trauma. Exclusion Criteria: - Patient is unable to sign or understand the consent form. - Patient is on any dialysis. - Patient has trauma related shortness of breath (i.e. penetrating wounds, crush injury). |
Observational Model: Cohort, Time Perspective: Prospective
Country | Name | City | State |
---|---|---|---|
Germany | Charite- Universitatsmedizin Berlin | Berlin | |
Greece | Athens University Hospital Attikon | Athens | |
Italy | University La Sapienza | Rome | |
New Zealand | University of Otago | Christchurch | |
Poland | Clinical Military Hospital | Wroclaw | |
Switzerland | University Hospital Basel | Basel | |
United Kingdom | University of Leicester | Leicester | |
United States | University of Maryland | Baltimore | Maryland |
United States | The Cleveland Clinic | Cleveland | Ohio |
United States | Henry Ford Health System | Detroit | Michigan |
United States | University of Minnesota | Minneapolis | Minnesota |
United States | Virgina Commonwealth University | Richmond | Virginia |
United States | University of California, San Diego | San Diego | California |
United States | Veterans Affairs Medical Center | San Diego | California |
United States | University of California, San Francisco | San Francisco | California |
Lead Sponsor | Collaborator |
---|---|
Brahms AG |
United States, Germany, Greece, Italy, New Zealand, Poland, Switzerland, United Kingdom,
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