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Study of JK07 in Patients With Chronic Heart Failure — RENEU-HF  

Heart Failure With Preserved Ejection Fraction Clinical Trial

Official title:
A Phase 2 Randomized, Double-blind, Placebo-controlled Study to Assess the Safety and Efficacy of JK07 in Adults With Chronic Heart Failure (RENEU-HF)

Clinical Trial Summary

This is a Phase 2, randomized, double-blind, placebo-controlled, multiple dose study to assess the safety, tolerability, and efficacy of JK07 in participants aged 18-85 with heart failure. There will be 2 cohorts in this study: Cohort 1: Heart failure (HF) participants with left ventricular ejection fraction (LVEF) of ≤ 40%. Cohort 2: Heart failure (HF) participants with left ventricular ejection fraction (LVEF) > 40% and ≤ 65%. Participants in both cohorts will be randomized into either low dose JK07, high dose JK07 or placebo. Participants will have a 2:1 chance of receiving JK07 versus placebo.

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

  • Heart Failure
  • Heart Failure With Preserved Ejection Fraction
  • Heart Failure With Reduced Ejection Fraction
Clinical Trial Details
NCT number NCT06369298
Study type Interventional
Source Salubris Biotherapeutics Inc
Contact Amanda McEwen
Phone 617-584-3853
Email Info@SalubrisBio.com
Status Recruiting
Phase Phase 2
Start date March 28, 2024
Completion date June 30, 2026
View Details
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