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The Efficacy and Safety of Zhigancao Tang Granule for HFpEF of Qi-Yin Dificiency — HFpEF  

Heart Failure With Preserved Ejection Fraction Clinical Trial

Official title:
A Randomized，Double-blinded, Placebo-controlled Trial Evaluating the Efficacy and Safety of Zhigancao Tang Granule for HFpEF of Qi-Yin Dificiency

Clinical Trial Summary

This study was designed as a randomized, double blinded and placebo-controlled clinical trial. The aim of the study is to evaluate the efficacy and safety of Zhigancao Tang granule in patients with HFpEF of Qi-Yin dificiency.

Clinical Trial Description

Heart failure with preserved ejection fraction (HFPEF) is a clinical syndrome characterized by diastolic dysfunction.The incidence of HFpEF is increasing in recent years. Standard treatment of heart failure does not improve the prognosis of HFPEF patients. Zhigancao Tang was used to improve the symptoms of chronic heart failure in China.This randomized,double-blinded and placebo-controlled trial will objectively and standardly evaluate the effectiveness and safety of Zhigancao Tang granule.After 12 weeks of treatment, 122 HFpEF patients with deficiency of Qi and Yin were observed and evaluated in terms of heart function, clinical symptoms,exercise tolerance and quality of life. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT04317339
Study type Interventional
Source Shanghai University of Traditional Chinese Medicine
Contact Bing Deng, M.D
Phone 8618917763110
Email dengbing82@sina.com
Status Not yet recruiting
Phase Phase 2
Start date March 20, 2020
Completion date March 31, 2022
View Details
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