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Heart Diseases clinical trials

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NCT ID: NCT05349773 Completed - Clinical trials for Ischemic Heart Disease

The Pneumatic Tourniquet Technique for Endoscopic Radial Artery Harvest; Does it Affect Patient Hemodynamics?

Start date: May 19, 2022
Phase:
Study type: Observational

This study aims to investigate the effect of the pneumatic tourniquet technique on the patients' hemodynamics; heart rate (HR), systolic blood pressure (SBP) and diastolic blood pressure (DBP).

NCT ID: NCT05348395 Recruiting - Heart Diseases Clinical Trials

Monocyte Priming When Consuming a Western Diet

Start date: January 6, 2023
Phase: N/A
Study type: Interventional

To determine the mechanism of monocyte priming in humans, the study team will conduct a complete feeding trial in normal weight and metabolically healthy human subjects (20-45 years of age) using a western diet (WD), characterized as being high-saturated fat, high-fructose, and high-calorie for 8 weeks.

NCT ID: NCT05347069 Recruiting - Clinical trials for Coronary Artery Disease

Efficacy and Safety of Aspirin in Patients With Chronic Coronary Syndromes Without Revascularization

ASA-IN
Start date: June 14, 2022
Phase: Phase 4
Study type: Interventional

The purpose of this study is to evaluate the efficacy and safety aspirin in patients with chronic coronary syndromes without revascularization.

NCT ID: NCT05344872 Completed - Clinical trials for Congenital Heart Disease

ATC Vs PSV for Ventilatory Weaning of Pediatrics Postcardiac Surgery

Start date: April 15, 2022
Phase: N/A
Study type: Interventional

The ventilator modality of automatic tube compensation (ATC) can provide variable pressure supports during the weaning process to overcome any change in the resistance of the breathing circuit, endotracheal tube, and airways. The aim of the study is to evaluate the automatic tube compensation (ATC) as a tool for ventilatory weaning in pediatrics after surgeries for congenital cardiac anomalies.

NCT ID: NCT05344547 Completed - Cardiac Disease Clinical Trials

Women With Polycystic Ovary Syndrome Are at High Risk for Cardiac Insults

Start date: March 21, 2020
Phase:
Study type: Observational

Objectives: Evaluation of the cardiovascular (CV) risk in a sample of CV asymptomatic infertile women with polycystic ovary syndrome (PCOS). Patients & Methods: 100 infertile PCOS women older than 30 years (PCOS group) and 50 fertile non-PCOS women (Non-PCOS group) underwent gynecological and laboratory diagnosis and then underwent a diagnostic protocol consisting of determination of body mass index (BMI), Homeostasis model assessment of insulin resistance (HOMA-IR) scoring and cardiologic evaluation using echocardiography, estimation of carotid artery intima-media thickness (CIMT), coronary artery calcium (CAC) score using multi-slice non-contrast cardiac CT and cardiac risk ratio (CRR). Study outcomes included the incidence of abnormal cardiac risk parameters and the determination of the best minimally invasive modality to be used as a screening test for these women.

NCT ID: NCT05340972 Recruiting - Heart Diseases Clinical Trials

Evaluate the Predictive Impact of the MEESSI Score

MEESSI
Start date: January 15, 2009
Phase:
Study type: Observational

Our primary purpose is to assess MEESSI score in predicting mortality and readmission of patients managed for acute heart failure (AHF) in Emergency Department. European Society of Cardiology recommend risk stratification for patients with AHF.

NCT ID: NCT05337644 Completed - Obesity, Morbid Clinical Trials

Indocyanine Green Test for Evaluation of Perfusion of Staple Line of the Stomach During Laparoscopic Sleeve Gastrectomy

Start date: January 21, 2022
Phase:
Study type: Observational

The investigators present the case of a 40-year-old female underwent laparoscopic sleeve gastrectomy. Intraoperative indocyanine green test was performed

NCT ID: NCT05335954 Completed - Hypotension Clinical Trials

Therapeutic Study Evaluating the Efficacy of Noradrenaline in the Prevention of Hypotension Related to Intubation for Cardiac or Thoracic Surgery

EPITUBE-HEART
Start date: April 27, 2022
Phase: Phase 3
Study type: Interventional

Arterial hypotension during general anaesthesia (GA) is a serious event. While hypotension can occur during surgery, it usually occurs following induction of GA (i.e. following the injection of drugs to enable intubation). This is due to the injection of large doses of anaesthetic drugs with a vasodilatory effect over a short period of time to induce a deep sleep to allow intubation to take place for artificial ventilation. The prevention of hypotension during surgery has been extensively studied. In contrast, the prevention of hypotension following GA induction has been the subject of only two randomised studies in the ICU and three non-randomised studies in the OR with small numbers of patients. The level of evidence for the use of noradrenaline in the operating theatre remains low. The hypothesis of the study is that noradrenaline initiated during preoxygenation can reduce the incidence of hypotension during induction of general anaesthesia.

NCT ID: NCT05335902 Recruiting - Cardiac Disease Clinical Trials

Optic Nerve Sheath After Extracorporeal Circulation

Start date: November 22, 2021
Phase:
Study type: Observational

The purpose of this study is to assess the influence of extracorporeal circulation during cardiac surgery on the optic nerve sheath diameter (ONSD) after the surgery.

NCT ID: NCT05332860 Completed - Clinical trials for Congenital Heart Disease

Extubation Times in Postoperative Congenital Cardiovascular Surgeries

Start date: May 1, 2020
Phase:
Study type: Observational [Patient Registry]

Background: Anesthesia management in pediatric cardiac surgeries focuses on reducing morbidity and mortality, early mobilization and discharge, using health resources sparingly and increasing the quality of life of patients. The duration of postoperative mechanical ventilation is one of the most important factors affecting the process after pediatric cardiac surgery. Besides the view that postoperative mechanical ventilation is safe, there are opposing views that it causes an increase in complications; It caused disagreements about extubation times. In our study, we aimed to investigate the factors affecting extubation times after pediatric cardiac surgery. Methods: 72 ASA≥III pediatric patients undergoing cardiac surgery with cardiopulmonary bypass were included in our study. The patients were divided into 3 groups according to their extubation time. Those that were extubated in the operating room (OR) or in 6 hours after surgery (Immediate Extubation or IE), those that were extubated within 6-48 hours of admission to the ICU (Early Extubation or EE) and those that were extubated sometime after 48 hours or not extubated (Delayed Extubation or DE). Many variables of preoperative, peroperative and postoperative periods were recorded to see which factors correlated with extubation times.