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Heart Diseases clinical trials

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NCT ID: NCT02865798 Not yet recruiting - Clinical trials for Heart Valve Diseases

China Senile Valvular Heart Disease Cohort Study

Start date: September 2016
Phase: N/A
Study type: Observational

Valvular heart diseases (VHD) are the most common causes of mortality and morbidity after coronary artery disease, hypertension, and heart failure, especially in senile patients who have more comorbidities and often require intervention. The prevalence of senile VHD is increased gradually as the growth of the age. In addition important changes have occurred as regards the presentation and treatment of the disease over recent years. However, there is little information about senile VHD in China. The purposes of this study are to evaluate the clinical characteristics, reasons for hospitalization, risk stratification, treatment modalities, quality of life and outcomes of senile hospitalized patients with VHD, to determine the risk factors affecting the prognosis, further to lay the foundation for establishing a prognosis model suitable for Chinese senile VHD.

NCT ID: NCT02864771 Active, not recruiting - Heart Disease Clinical Trials

Scandinavian Multicenter Study to Advance Risk Stratification in Heart Disease- Ventricular Arrhythmias

SMASH 1
Start date: August 2016
Phase:
Study type: Observational

The purpose of this study is to identify markers of increased risk for incident ventricular arrhythmias and cardiovascular events in patients already being treated with an implantable cardioverter-defibrillator (ICD) by exploring patient history and clinical findings, biological markers, ECG markers, and echocardiographic markers.

NCT ID: NCT02861365 Completed - Cardiac Disease Clinical Trials

Myocardial Perfusion and Scarring in Adults With Congenital Heart Disease

Start date: July 2013
Phase:
Study type: Observational

This is a study of the perfusion of the myocardium in adults with specific forms of repaired congenital heart disease using established cardiac MRI techniques and correlating perfusion with clinical outcomes.

NCT ID: NCT02855554 Recruiting - Clinical trials for Cardiomyopathy, Myocarditis, Ischemic Heart Disease

Quantitative Cardiac Parametric Mapping

Myomapping
Start date: June 20, 2014
Phase: N/A
Study type: Interventional

The overall goal of this project is to evaluate the clinical potential of fast quantitative myocardial tissue characterization using recently emerged Cardiac Magnetic Resonance Imaging (CMR) techniques to aid the diagnosis, treatment, and follow up of patients with myocardial diseases, such as ischemic heart disease, cardiomyopathies, and myocarditis.

NCT ID: NCT02852031 Recruiting - Clinical trials for Hypoplastic Left Heart Syndrome (HLHS)

National Collaborative to Improve Care of Children With Complex Congenital Heart Disease

NPC-QIC
Start date: May 2016
Phase:
Study type: Observational [Patient Registry]

The purpose of this initiative is to improve care and outcomes for infants with HLHS by expanding the NPC-QIC national registry to gather clinical care process, outcome, and developmental data on infants with HLHS between diagnosis and 12 months of age, by improving the use of standards into everyday practice across pediatric cardiology centers, and by engaging parents as partners in the process.

NCT ID: NCT02850627 Recruiting - Clinical trials for Acute Myocardial Infarction

The Effect of Tongguan Capsule for MicroRNA Profiles in Coronary Heart Disease Patients

Start date: July 2016
Phase: Phase 4
Study type: Interventional

The purpose of this study is to test the expression of microRNAs related to the syndromes after the intervention of Tongguan capsule,preliminarily to investigate the mechanism of the effects of Tongguan capsule, and provide the biological foundation of curative effect of Tongguan capsule.

NCT ID: NCT02849067 Completed - Clinical trials for Ischaemic Heart Disease

Hemodynamic Responses of Stable Ischemic Heart Disease Patients to a Comedy Session

Start date: May 25, 2015
Phase: N/A
Study type: Interventional

It is known that laughter can bring benefits in terms of physiological and psychological parameters, in addition to improving the individual's quality of life. However, the literature is still scarce as to the existence of studies investigating the effects of a comedy film specifically in hemodynamics.

NCT ID: NCT02848859 Completed - Insomnia Clinical Trials

Improving Sleep for Healthy Hearts

Start date: March 2015
Phase: N/A
Study type: Interventional

This is a pilot study randomizing patients with insomnia and coronary heart disease to either general sleep hygiene counseling and web-based cognitive behavioral therapy for insomnia versus general sleep hygiene counseling alone (followed by the cognitive behavioral therapy at a later date).

NCT ID: NCT02844270 Active, not recruiting - Heart Diseases Clinical Trials

Galaxy Rapamycin Drug-Eluting Bioresorbable Coronary Stent System First-in-man Study

Start date: August 9, 2016
Phase: N/A
Study type: Interventional

The Galaxy First-in-man study is a small pilot. single arm research , which will enroll a total of 45 patients. The goal is to access the feasibility, safety and efficacy of Rapamycin Drug-Eluting Bioresorbable Coronary Stent System in the treatment of patients with de novo coronary lesion.

NCT ID: NCT02841774 Completed - HIV Infection Clinical Trials

High Intensity Lipid Lowering Following Acute Coronary Syndromes for Persons Living With HIV

HILLCLIMBER
Start date: November 2016
Phase: Phase 2
Study type: Interventional

HILLCLIMBER is a randomized, controlled, open-label phase II trial of moderate dose statin therapy (pravastatin 40mg daily) versus high-dose statin therapy (rosuvastatin 20-40mg daily) in HIV-infected persons taking antiretroviral therapy (ART) who have coronary heart disease (CHD).