Body Water Content in Cyanotic Congenital Heart Disease

Status Completed

Clinical Trial Summary

Adults with cyanotic congenital heart disease have elevated levels of plasma proatrial natruretic peptide (proANP) which most likely results in chronic dehydration, leading to reduced oxygen transport to tissues and shortness of breath with activity. The purpose of this study is to characterize adults with cyanotic congenital heart defects with respect to their body composition (water and fat-free mass) and resting metabolic rates. The study consists of several measures of how much body water, fat and lean tissue a subject has, and measures the number of calories the subject's body uses at rest. Adult subjects with cyanotic congenital heart disease will be recruited along with healthy noncyanotic control subjects matched for age, gender, and body weight.

Clinical Trial Description

n/a

Study Design

Observational Model: Case Control

Related Conditions & MeSH terms

Clinical Trial Details

NCT number	NCT00000107
Study type	Observational
Source	National Center for Research Resources (NCRR)
Contact
Status	Completed
Phase	N/A

View Details

See also
Status	Clinical Trial	Phase
Recruiting	`NCT05330338` - Genetics of Ventriculo-arterial Discordance	N/A
Withdrawn	`NCT03405636` - Xeltis Pulmonary Valved Conduit Safety and Performance Study	N/A
Completed	`NCT02443662` - Colloid Osmotic Pressure in Patients With Fontan Circulation
Terminated	`NCT02519335` - Use of the Cardioprotectant Dexrazoxane During Congenital Heart Surgery: Proposal for Pilot Investigation	Phase 1
Completed	`NCT01835392` - Neuroprotective Effects of Remote Ischemic Preconditioning (RIPC) During Infant Cardiac Surgery	N/A
Completed	`NCT00371891` - Ontario Multidetector Computed Tomographic (MDCT) Coronary Angiography Study (OMCAS)	Phase 4
Completed	`NCT03035552` - CTICU Pacifier Activated Music Player and Mother's Voice	N/A
Recruiting	`NCT04581668` - Impact of NAVA Ventilation on Brain Oxygenation and Perfusion in Children With Congenital Heart Disease	N/A
Enrolling by invitation	`NCT04866537` - Evaluation of the Diagnostic Performance of Specialized Fetal Cardiac Ultrasound in the CPDPN - Arc Alpin Network
Completed	`NCT03049540` - Effect of Phosphodiesterase-5 Inhibition With Tadalafil on SystEmic Right VEntricular Size and Function	Phase 3
Completed	`NCT02377674` - Safety and Performance of the COR-VG-001 Conduit in Pediatric Patients for Extracardiac Total Cavopulmonary Connection	N/A
Completed	`NCT01679275` - Pre-operative Cerebral Oxygenation in Neonates With Congenital Heart Disease
Terminated	`NCT00543309` - Effects of Perioperative Nesiritide or Milrinone Infusion on Recovery From Fontan Surgery	Phase 2
Completed	`NCT03957512` - Livet Skal Leves (A Life to Live)
Recruiting	`NCT06005428` - Effectiveness of CRD-4730 in Participants With Catecholaminergic Polymorphic Ventricular Tachycardia (CPVT)	Phase 2
Recruiting	`NCT02691689` - Genes Associated With Development of Pulmonary Arterial Hypertension in Patients With Congenital Shunt Lesions	N/A
Completed	`NCT02306057` - Fluid Balance in Children Undergoing Fontan Surgery	N/A
Recruiting	`NCT02157597` - NIRS Guidance Trail in Children's Heart Surgery	N/A
Completed	`NCT01570933` - Feasibility Study Over the NAVA Mode in Noninvasive Ventilation After Cardiac Surgery in Infants.	Phase 4
Completed	`NCT00396877` - Efficacy And Safety Of Clopidogrel In Neonates /Infants With Systemic To Pulmonary Artery Shunt Palliation	Phase 3