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Hearing Loss clinical trials

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NCT ID: NCT04397354 Completed - Clinical trials for Hearing Loss, Sensorineural

Intracochlear Dexamethasone Application During Cochlear Implantation for Preserving Cochlear Cells

Start date: March 2, 2020
Phase: N/A
Study type: Interventional

The protection of cochlear cells is one of the main concerns of cochlear implant surgery. New electrode designs or additional molecules have been used for this purpose. The aim of the study is to test the effect of dexamethasone in two different application methods.

NCT ID: NCT04374851 Completed - Hearing Loss Clinical Trials

A Comparative Clinical Investigation of Two Hearing Instrument Digital Signal Processing

Start date: August 3, 2020
Phase: N/A
Study type: Interventional

The purpose of this study is to show that the performance of the new digital signal processing system is better than the system used in the currently CE marked devices. Speech in narrowband noise and acceptable levels of noise should be improved with the new system, and speech understanding overall should not be negatively affected. There should be no artefacts or unwanted noises caused by the new system.

NCT ID: NCT04331015 Completed - Clinical trials for Sensorineural Hearing Loss

Artificial Intelligence in Diagnosis of DFNA9

DFNA9
Start date: February 1, 2020
Phase:
Study type: Observational

To study the positive predictive value of Audiogene v.4.0 open source online machine learning tool in accurately predicting DFNA9 (DeaFNess autosomal dominant ninth) as top 3 gene loci in a large series of genetically confirmed c.151C>T,p.Pro51Ser (p.P51S) variant carriers in COCH (coagulation factor C Homology).

NCT ID: NCT04320407 Completed - Clinical trials for Conductive Hearing Loss

Osia CPT Code Study

Start date: September 30, 2020
Phase: N/A
Study type: Interventional

To evaluate the clinical efficacy of the Osia 2 system in patients with conductive or mixed conductive hearing loss in a US cohort.

NCT ID: NCT04291274 Completed - Clinical trials for Long Term Neurobehavioral Effects

The Neurobehavioral Effects of Anesthetics on Infants With Hearing Impairment(Retrospective Research)

Start date: November 1, 2019
Phase:
Study type: Observational

The long-term effect of general anesthesia on developing brain is the focus of clinicians when infants exposed to general anesthesia for a long time during operation. A retrospective study showed that children exposed to long-term or repeated operations, the anesthetics had a higher incidence of cognitive impairment in adolescence than those did no. When infants with hearing impairment undergo bilateral cochlear implant surgery, they are at high risk of long-term neurobehavioral abnormalities caused by anesthesia. In this study, investigators intend to observe the long-term behavioral abnormalities of hearing-impaired infants after intravenous or inhalation anesthesia by a ambispective cohort study.

NCT ID: NCT04284384 Completed - Dementia Clinical Trials

Hearing Impairment as a Risk Factor for Dementia in Older Adults

Start date: August 19, 2019
Phase:
Study type: Observational

This Doctor of Philosophy (PhD) project is part of a larger project on potentially modifiable risk factors for dementia in a life course perspective, with an overarching aim to improve prevention of dementia and thereby potentially relieve patient and caregiver distress and decrease societal load. The present PhD project will concentrate on confirming knowledge of HI as an independent risk factor for dementia and exploring potentially causative factors to explain this relationship.

NCT ID: NCT04281953 Completed - Cancer Clinical Trials

Impact on Quality of Life of Long-term Ototoxicity in Cancer Survivors

Start date: September 5, 2019
Phase:
Study type: Observational

This project aims to explore, in depth, the burden of hearing loss and tinnitus on cancer survivors. Using semi-structured interviews, audiograms and a variety of validated questionnaires, the specific impact ototoxicity has on quality of life will be investigated. From this, we can identify the specific needs of patients experiencing hearing loss and tinnitus following chemotherapy and develop a tailored and personalised support system.

NCT ID: NCT04271761 Completed - Hearing Impairment Clinical Trials

Evaluation of Carina Microphone Sensitivity and Maximum Stable Gain in Adult Recipients

CAMSEN
Start date: February 11, 2020
Phase:
Study type: Observational

This investigation is a single-centre, prospective, single-arm, post-market, non-interventional, pilot clinical investigation designed to characterize microphone sensitivity and maximum stable gain of the Cochlear Carina System.

NCT ID: NCT04241679 Completed - Clinical trials for Sensorineural Hearing Loss

Auditory Nerve Test System During Vestibular Schwannoma Resection

ANTS
Start date: January 20, 2020
Phase: N/A
Study type: Interventional

The Auditory Nerve Test System (ANTS) is a novel device that stimulates the auditory nerve much like a cochlear implant. The purpose of this study is to demonstrate feasibility of the ANTS during translabyrinthine surgery for vestibular schwannoma resection. If the auditory nerve is kept intact, then the patients will also receive a cochlear implant at the same time potentially alleviating the morbidities caused by a vestibular schwannoma and asymmetric sensorineural hearing loss.

NCT ID: NCT04241302 Completed - Deafness Clinical Trials

Development of a Mobile App FFVT vs FFCT : A RCT

Start date: January 1, 2020
Phase: N/A
Study type: Interventional

This is an open-labelled randomised controlled trial involving 2 groups which are Free Field voice test vs Free Field Click tests using digital hand-held devices. This study will be done at a sound-proof room in ORL clinic in Hospital Sultanah Aminah, Johor, Malaysia from January till July 2020.