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Clinical Trial Details — Status: Completed

Administrative data

NCT number NCT06449300
Other study ID # 2021.11.07
Secondary ID
Status Completed
Phase N/A
First received
Last updated
Start date November 11, 2021
Est. completion date January 11, 2024

Study information

Verified date June 2024
Source Princess Nourah Bint Abdulrahman University
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This study explores the effects of varying volumes of resistance training on body composition, strength, peak power, and muscle thickness in untrained women over eight weeks. A randomized controlled trial involving 45 female college students assessed the outcomes across three groups: low-volume training (LVT) with three weekly sessions, moderate-volume training (MVT) with four weekly sessions, and high-volume training (HVT) with five weekly sessions. Participants were untrained, aged 18-65, and free from cardiovascular diseases or performance-enhancing drugs. The hypothesis suggested that moderate volume training would yield optimal muscle development, considering the potential non-linear dose-response relationship where excessive training might be detrimental. Measurements included body composition, muscle thickness, and peak power through a force platform during vertical jumps. Data analysis focused on changes in muscle thickness, strength, and body composition, with statistical significance set at p < 0.05. The study aimed to provide insights into how different training volumes affect physiological adaptations in untrained women, potentially guiding fitness regimen optimizations for similar populations.


Description:

The study aimed to investigate the effect of different resistance training volume (low-, moderate, and high) on body composition, maximal strength, peak power, and muscle thickness in untrained women over eight weeks. The study is a three-arm, randomized controlled trial, 45 female college students participated, fit the specific inclusion criteria like age between 18-65 and being untrained. Exclusion criteria included the use of performance-enhancing drugs or recent resistance training. Participants were randomly assigned to one of three groups: low-volume training (LVT) with three sessions weekly, moderate-volume training (MVT) with four sessions weekly, and high-volume training (HVT) with five sessions weekly. Each session comprised 12 exercises. Split split-strength training method was applied. After participants' 1RM maximums were determined, training loads were calculated separately for each participant. All workouts were conducted by certified trainers to ensure they were performed in the correct training format. Each training session lasted approximately 60 minutes. The weekly training loads of all participants were increased by 5%. In the LVT group, 3 sets of 8-12 repetitions of: between sets interval: 120 seconds (3 days/wk), in the MVT group, 3 sets of 8-12 repetitions of: between sets interval: 120 seconds (4 days/wk), in the HVT group, 3 sets of 8-12 repetitions of: between sets interval: 120 seconds exercises (5 days/wk) were performed. Results and data analysis involved anthropometric measurements, muscle thickness via ultrasound, and peak power from the vertical jump test. Statistical significance was set at p < 0.05, and effect sizes were calculated with Partial Eta Squared values.


Recruitment information / eligibility

Status Completed
Enrollment 15
Est. completion date January 11, 2024
Est. primary completion date December 11, 2023
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 65 Years
Eligibility Inclusion Criteria: - Adult women between ages of 18 -65 years old - Able to walk independently - Free of any history of cardiovascular disease - Untrained (less than 150 min of PA/week) Exclusion Criteria: - Intake of performance-enhancing drugs, anabolic steroids - Any history of injury, or physiological or physical limitations that could affect the ability to perform training and physical testing in the last year. - Those who had been RT for more than 2 months in the previous 6 months were excluded.

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Resistance exercise-LVT
(low volume training - 3 sessions of 12 exercises per week)
Resistance exercise-MVT
(moderate volume training - 4 sessions of 12 exercises per week)
Resistance exercise-HVT
(high volume training - 5 sessions of 12 exercises per week)

Locations

Country Name City State
Saudi Arabia Princess Nourah bint Abdulrahman University Riyadh

Sponsors (2)

Lead Sponsor Collaborator
Princess Nourah Bint Abdulrahman University Kirikkale University

Country where clinical trial is conducted

Saudi Arabia, 

Outcome

Type Measure Description Time frame Safety issue
Primary Body height measurements A stadiometer is attached to the wall. It has a sliding horizontal headpiece that's adjusted to rest on top of your head. The measurement of height will be conducted using a Mesilife portable stadiometer. at baseline and end of 8 week
Primary Anthropometric measurements Bio-impedance body composition analysis system at baseline and end of 8 week
Primary Muscle thickness measurements A portable ultrasound scanner will be used to determine muscle thickness. At one location, muscle thickness will be measured: Between the greater trochanter and the lateral epicondyle of the thigh, the thickness of the quadriceps femoris (Vastus lateralis) will be measured at 50%. Ultrasound tests will be done at the start of the study and 8 weeks later, by a researcher blinded to the interventions. All tests were performed in the morning when participants are fasting. at baseline and end of 8 week
Primary Countermovement Jump (CMJ) Countermovement Jump (CMJ) values of all participants will be measured. Peak muscle power measures in watts (W) using the Accupeak power2.0 portable force platform system . The measurement frequency of the device was set to 500 Hz. Participants will undrergo a 10-minute warm-up program before completing a CMJ. Participants will be asked to begin a downward movement and jump as high as possible after hearing a tone from the computer. at baseline and end of 8 week
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