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A First in Human Trial Evaluating THB335 in Healthy Participants

Healthy Clinical Trial

Official title:
A Randomized, Double-Blind, Placebo-Controlled, Phase 1, Single and Multiple Ascending Dose Study to Assess the Safety, Pharmacokinetics, Pharmacodynamics, and Food Effect of THB335 in Healthy Participants

Clinical Trial Summary

This study is a double blind, randomized, placebo-controlled, Phase 1 study in two parts: single ascending doses and food effect (Part 1) and multiple ascending doses (Part 2).

Clinical Trial Description

THB335 is a highly potent and selective inhibitor of the receptor tyrosine kinase KIT that is expressed on mast cells. The study will evaluate the safety, pharmacokinetics, pharmacodynamics, and food effect profile of THB335 administered orally in healthy participants. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06425861
Study type Interventional
Source Third Harmonic Bio, Inc.
Contact Third Harmonic Bio
Phone 617-915-6680
Email info@thirdharmonicbio.com
Status Recruiting
Phase Phase 1
Start date May 2, 2024
Completion date March 15, 2025
View Details
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