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Clinical Trial Details — Status: Recruiting

Administrative data

NCT number NCT06096610
Other study ID # STUDY0014990
Secondary ID
Status Recruiting
Phase N/A
First received
Last updated
Start date August 1, 2023
Est. completion date October 1, 2024

Study information

Verified date October 2023
Source University of Kansas Medical Center
Contact Trent J Herda
Phone 17858642224
Email t.herda@ku.edu
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

The project is going to examine the effects of resistance exercise training in prepubescent youth on skeletal muscle strength and lipid content.


Recruitment information / eligibility

Status Recruiting
Enrollment 35
Est. completion date October 1, 2024
Est. primary completion date October 1, 2024
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 8 Years to 10 Years
Eligibility Inclusion Criteria: - Healthy volunteer males and females ages 8 - 10 years. Exclusion Criteria: - No history or ongoing neuromuscular diseases. - No history or ongoing musculoskeletal injuries. - No history or ongoing disease that effects metabolism.

Study Design


Related Conditions & MeSH terms


Intervention

Other:
Resistance exercise training
Participants will strength train via linear periodization resistance exercise training.

Locations

Country Name City State
United States Hoglund Biomedical Imaging Center Kansas City Kansas
United States Exercise and Human Performance Laboratory Overland Park Kansas
United States Metabolic and Body Composition Laboratory Overland Park Kansas

Sponsors (2)

Lead Sponsor Collaborator
University of Kansas Medical Center National Strength and Conditioning Association Foundation

Country where clinical trial is conducted

United States, 

Outcome

Type Measure Description Time frame Safety issue
Other Change from baseline in intramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy The score will reflect a concentration. The higher score, reflects more fat in the fibers. baseline, following the intervention (9 weeks)
Other Change from baseline in extramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy The score will reflect a concentration. The higher score, reflects more fat in the fibers. baseline, following the intervention (9 weeks)
Other Change from baseline in the fatty acid saturation levels of the extramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy The score will reflect a saturation level of fatty acids in the extramyocellular lipid. The higher score, reflects greater fatty acid saturation. baseline, following the intervention (9 weeks)
Other Change from baseline in the fatty acid saturation levels of the intramyocellular lipids of the vastus lateralis, as measure with magnetic resonance spectroscopy The score will reflect a saturation level of fatty acids in the intramyocellular lipid. The higher score, reflects greater fatty acid saturation. baseline, following the intervention (9 weeks)
Primary Change in the muscular strength of leg extensors, as measured with isotonic strength. The score will reflect the strength of the leg extensors. The higher score, reflects greater muscular strength. baseline, following the intervention (9 weeks)
Secondary Change from baseline in thigh muscle cross-sectional area. Scores are measured cross-sectional area from ultrasound images. The higher score, reflects greater muscle size of the leg extensors. baseline, following the intervention (9 weeks)
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