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CIRcadian Rhythms and CortisoL. Effects on Substrate Metabolism and Clock Gene Expression and Functioning — CIRCLE  

Healthy Clinical Trial

Official title:
CIRcadian Rhythms and CortisoL. Effects on Substrate Metabolism and Clock Gene Expression and Functioning

Clinical Trial Summary

The aim of this project is to study the effects of exogenous glucocorticoid exposure on substrate metabolism, energy expenditure and correlates of circadian rhythmicity in healthy adults. The hypotheses are: Short-term high dose glucocorticoid exposure in healthy subjects disrupts: - The inherent circadian pattern of the respiratory exchange ratio and REE - Sleep quality, appetite and food intake - Clock gene expression and function in adipose tissue, skeletal muscle and blood leukocytes

Clinical Trial Description

n/a

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT06035081
Study type Interventional
Source University of Aarhus
Contact Simon B Hansen, MD
Phone 41111574
Email simhan@clin.au.dk
Status Recruiting
Phase N/A
Start date September 15, 2023
Completion date March 2024
View Details
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