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Clinical Trial Summary

Explore the shared or separated neural mechanisms of social exclusion and social segregation and compare differential effects of AVP and OXT on these social interaction function.


Clinical Trial Description

A large body of research has shown that there are differences in the neural representation between social exclusion and social segregation, but the results are inconsistent, and the exploration of the neural basis is still insufficient. In addition, there are two mainstream theoretical explanations for these differences, namely the construction-level theory and the emotion-based theory, but there is no consistent theoretical model yet. Therefore, further exploration is necessary to confirm the cognitive and neural mechanisms underlying the differences between social exclusion and social segregation, and to attempt to reveal the theoretical explanations for these differences. In this project, the investigators propose to perform behavioral and functional magnetic resonance imaging (fMRI) techniques to examine the shared or separate neural mechanisms of social exclusion and social segregation (exp 1: social exclusion; exp 2: social separation) and investigate the modulatory effects of OXT/AVP on them (PLC/24IU OXT/20IU AVP). ;


Study Design


Related Conditions & MeSH terms


NCT number NCT05920707
Study type Interventional
Source University of Electronic Science and Technology of China
Contact Keith M Kendrick, Dr
Phone +86-28-61830811
Email k.kendrick.uestc@gmail.com
Status Recruiting
Phase N/A
Start date April 20, 2023
Completion date October 1, 2023

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