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Feasibility, Safety and Utility of Endomicroscopy to Study the Intestines of Unsedated Infants at University of Virginia (UVa)

Healthy Clinical Trial

Official title:
Feasibility, Safety and Utility of Endomicroscopy to Study the Intestines of Unsedated Infants at UVa

Clinical Trial Summary

The purpose of this study is to demonstrate the feasibility of using the transnasal endomicroscopy (TNE) platform, using intestinal potential difference (IPD) and microbiome brush to evaluate the intestine of unsedated infants.

Clinical Trial Description

A total of fifteen (15) subjects, infants 6 months of age to 48 months of age will be enrolled in this study. While the subject is awake and unseated, a catheter with optical coherence tomography (OCT) imaging technology will be introduced transnasally. Images will be acquired while the tube is moved through the subject's GI tract. After imaging is complete, accessory device(s) may be threaded through the catheter to collect samples of the gut microbiome and/or measure intestinal potential difference. ;

Study Design

Related Conditions & MeSH terms

Clinical Trial Details
NCT number NCT05857488
Study type Interventional
Source Massachusetts General Hospital
Contact
Status Enrolling by invitation
Phase N/A
Start date January 1, 2022
Completion date December 31, 2023
View Details
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