Healthy Clinical Trial
Official title:
Evaluate the Exposure to Toxicants Emitted During a Structural Fire Assessed by Urinary and Buccal Cell Biomarkers Found in Firefighters.
Observational, within subject study design with 1 pre and 2 post-fire exposure biomarker samples collected to assess exposure to toxicants from combustion emissions related to fighting a structural fire.
| Status | Recruiting |
| Enrollment | 60 |
| Est. completion date | December 31, 2025 |
| Est. primary completion date | December 31, 2024 |
| Accepts healthy volunteers | Accepts Healthy Volunteers |
| Gender | All |
| Age group | 18 Years and older |
| Eligibility | Inclusion Criteria: - Firefighter (career or volunteer) - Over 18 years of age - Able to provide written voluntary consent Exclusion Criteria: - Unwilling to provide a pre and post-exposure urine sample - Current cancer diagnosis - Tobacco use within the last 1 year (verified by urinary TNEs) |
| Country | Name | City | State |
|---|---|---|---|
| United States | Masonic Cancer Center | Minneapolis | Minnesota |
| Lead Sponsor | Collaborator |
|---|---|
| Masonic Cancer Center, University of Minnesota |
United States,
| Type | Measure | Description | Time frame | Safety issue |
|---|---|---|---|---|
| Primary | Studying biomarker levels in firefighters pre and post fire call. | The investigators will evaluate the differences between mean pre-exposure biomarker levels and post-exposure levels in urine and buccal samples collected within 24 hours post-exposure and 1-week post-exposure respectively using t-tests to test for statistical significance. | 48 months |
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