Effects of Combinations of Performance-enhancing Supplements on Exercise Performance

Healthy Clinical Trial

Official title:

Effects of Different Combinations of Performance-enhancing Supplements on High Intensity Exercise Performance

Clinical Trial Details — Status: Active, not recruiting

Administrative data

• NCT number: NCT05354999
• Other study ID #: COCKTAIL
• Status: Active, not recruiting
• Phase: N/A
• Start date: April 18, 2022
• Est. completion date: December 2023

Study information

• Verified date: August 2022
• Source: University of Copenhagen
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

The purpose of the study is to investigate the effect of combinations of creatine monohydrate, sodium bicarbonate and caffeine on exercise performance and fatigability.

Recruitment information / eligibility

• Status: Active, not recruiting
• Enrollment: 23
• Est. completion date: December 2023
• Est. primary completion date: March 2023
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 45 Years

Eligibility

Inclusion Criteria:

• Healthy

• VO2max of >50 ml/min/kg for men and >45 ml/min/kg for women

• Performs endurance training >3 times per week

Exclusion Criteria:

• Chronic disease deemed by the study responsible medical doctor to interfere with any part of the study

• Smoking

• Chronic use of prescription medicine deemed by the study responsible medical doctor to interfere with any part of the study

Related Conditions & MeSH terms

• Healthy

Intervention

Dietary Supplement:
• Sodium bicarbonate and caffeine
On experimental days subjects ingest a combination of sodium bicarbonate, caffeine and placebo.

Locations

Country	Name	City	State
Denmark	August Krogh Building	Copenhagen

Sponsors (1)

Lead Sponsor	Collaborator
Morten Hostrup, PhD

Country where clinical trial is conducted

Denmark, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Work performed (kJ/Watt)	Work performed during a 6 minute time trial	Measured at each trial throughout the study, on average 4 weeks
Secondary	Work performed (kJ/Watt)	Work performed during a 15 second sprint test	Measured at each trial throughout the study, on average 4 weeks
Secondary	Muscle strength (Nm)	Maximal voluntary isometric contraction of m. quadriceps femoris	Measured at each trial throughout the study, on average 4 weeks