Healthy Clinical Trial
Official title:
Phase I, Open-label, Single-sequence, Cross-over Study of the Effect of Multiple Doses of Itraconazole on Single-dose Tepotinib Pharmacokinetics in Healthy Participants
The purpose of this study is to assess the effect of multiple doses of itraconazole on singledose tepotinib pharmacokinetics in healthy participants. Study details include: Study Duration: up to 48 days Treatment Duration: single dose of tepotinib on Days 1 and 12, 11 days of treatment with itraconazole (Days 8 to 18) Visit Frequency: residence in the Clinical Research Unit from Days -1 to 4 and Days 11 to 15, ambulatory daily visits from Days 5 to 10 and 16 to 20
n/a
| NCT number | NCT05203822 |
| Study type | Interventional |
| Source | Merck Healthcare KGaA, Darmstadt, Germany, an affiliate of Merck KGaA, Darmstadt, Germany |
| Contact | Communication Center |
| Phone | +49 6151 72 5200 |
| [email protected] | |
| Status | Recruiting |
| Phase | Phase 1 |
| Start date | January 21, 2022 |
| Completion date | May 13, 2022 |
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