Healthy Clinical Trial
Official title:
Effect of 100% Orange Juice Intake on Subjective Appetite, Food Intake, Glycemic Response and Subjective Mood in Healthy Adults
Verified date | March 2023 |
Source | Ryerson University |
Contact | n/a |
Is FDA regulated | No |
Health authority | |
Study type | Interventional |
The purpose of this study is to determine the effects of 100% orange juice on short-term food intake (FI), satiety, post-prandial glycemia and mood in healthy adults. We hypothesize that the consumption of 100% orange juice in the pre-meal environment will improve satiety signals and mood, and suppress FI through its effect on post-prandial glycemia.
Status | Completed |
Enrollment | 36 |
Est. completion date | December 22, 2022 |
Est. primary completion date | December 22, 2022 |
Accepts healthy volunteers | Accepts Healthy Volunteers |
Gender | All |
Age group | 18 Years to 45 Years |
Eligibility | Inclusion Criteria: - aged 18-45 years; - within the healthy body mass index (BMI) range for adults of 18.5-24.9 kg/m2. Exclusion Criteria: - individuals who are dieting; - restrained eaters; - breakfast skippers; - those who dislike breakfast or lunch treatment foods; - those taking medication; - individuals with any metabolic disorders or significant weight fluctuations. |
Country | Name | City | State |
---|---|---|---|
Canada | Centre for Urban Innovation (CUI-109), School of Nutrition, Ryerson University | Toronto | Ontario |
Lead Sponsor | Collaborator |
---|---|
Ryerson University |
Canada,
Type | Measure | Description | Time frame | Safety issue |
---|---|---|---|---|
Primary | Change from baseline glycemic response (acute phase) | Blood glucose (mmol/L). Three drops of blood from the finger will be collected at each time point using a single-use, auto-disabling lancet device and sodium fluoride/potassium oxalate capillary blood collection tubes. Blood glucose will be measured using a YSI 2900D Biochemistry Analyzer (YSI Inc., Yellow Springs, OH). | Collected at baseline (0 minutes), 15 minutes, 30 minutes, 45 minutes, and 60 minutes post-treatment consumption | |
Primary | Rest-of-day blood glucose concentrations | Blood glucose (mmol/L). Rest-of-day blood glucose concentrations will be determined using a Dexcom G6 CGM system. | Continuous measurements for 24 hours post-treatment consumption | |
Primary | Ad libitum food intake | Lunch pizza meal. Food intake will be determined by weighing the meal before and after serving. The net weight of the test meal will be converted to calories. | At 60 minutes post-treatment consumption | |
Secondary | Change from baseline subjective appetite | Measured using visual analogue scales (VAS). Each VAS is a 100 mm line where they will place a pencil mark to describe their feelings. Questions will include desire to eat, fullness, hunger, and prospective food consumption. Individual questions will be used to form a composite score. | Collected at baseline (0 minutes), 15 minutes, 30 minutes, 45 minutes, and 60 minutes post-treatment consumption | |
Secondary | Change from baseline subjective emotions and mood | Measured using visual analogue scales. Each VAS is a 100 mm line where they will place a pencil mark to describe their feelings. Questions will measure aggression, anger, excitement, disappointment, frustration, alertness, sadness, tension, effort, happiness, weariness, calmness, sleepiness, and wellness. Individual questions will be used to form a composite score. | Collected at baseline (0 minutes), 15 minutes, 30 minutes, 45 minutes, and 60 minutes post-treatment consumption | |
Secondary | Rest-of-the-day food intake | Participants will be sent home with a rest-of-the-day food intake recall sheet to record their snacks, meals, and beverages.
Rest of day food log |
For the rest of the day following test session completion (1 day) | |
Secondary | Rest-of-the-day physical activity | Participants will be sent home with a rest-of-the-day physical activity recall sheet to record any activities performed.
Physical activity questionnaire |
For the rest of the day following test session completion (1 day) |
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