The Effect of Transcranial Direct Stimulation on Cognitive Functions of Healthy Adults

Healthy Clinical Trial

Official title:

The Effect Of Transcranial Direct Stimulation Applied To The Dorsolateral Prefrontal Cortex And Posterior Parietal Cortex İn Cognitive Function, Mood And Proprioception İn Healthy Adults

Clinical Trial Details — Status: Completed

Administrative data

• NCT number: NCT04873804
• Other study ID #: tDCS on DLPFC and PPC
• Status: Completed
• Phase: N/A
• Start date: October 10, 2019
• Est. completion date: June 10, 2020

Study information

• Verified date: May 2021
• Source: Medipol University
• Contact: n/a
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

Background: Transcranial direct current stimulation(tDCS) has been used to improve cognitive functions in healthy young adults. Purpose: To investigate the effect of TDCS application on different cortex regions on cognitive function. Methods: Sixty individuals aged 18-30 were included in the study. The participants were randomly divided into the left dorsolateral prefrontal cortex (Left DLPFC Group)(n=20), the right posterior parietal cortex (Right PPC Group)(n=20), and the sham group (Sham Group)(n=20). tDCS was applied for 20 minutes on weekdays for 2 weeks. The participants were evaluated in terms of cognitive functions with Neuropsychometric Test Battery before and after treatment.

Recruitment information / eligibility

• Status: Completed
• Enrollment: 57
• Est. completion date: June 10, 2020
• Est. primary completion date: May 10, 2020
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 30 Years

Eligibility

Inclusion Criteria:

• being 18-30 years old

Exclusion Criteria:

• alcohol and substance addiction
• previous mental illness
• having mental and cognitive problems
• a history of head trauma
• having cardiovascular disease.

Related Conditions & MeSH terms

• Cognitive Symptom
• Healthy
• Neurobehavioral Manifestations

Intervention

Other:
• Transcranial Direct Current Stimulation
The intervention protocols were applied using tDCS (Teknofil TESsaNova). All individuals received 2 mA of anodal tDCS for 2 weeks on weekdays. All applications were done in the form of 20-minute sessions.

Locations

Country	Name	City	State
Turkey	Damla Ören	Istanbul
Turkey	Medipol Mega Hospital	Istanbul

Sponsors (1)

Lead Sponsor	Collaborator
Medipol University

Country where clinical trial is conducted

Turkey, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	Neuropsychiatric Test Battery	It is a test battery for getting detailed information about general cognitive status.	3 weeks
Primary	Beck Depression Scale	It measures the symptoms seen in depression such as emotional, cognitive and motivational. It includes 21 items determine a behavioral feature related to depression. Items are numbered from 0 to 3. The goal is to objectively break down the degree of symptoms.; The total score of all answers is calculated as follows: 0 to 9 points: Minimally depressive symptoms 10 to 16 points: Mild depressive symptoms Between 17 and 29 points: Moderate depressive symptoms Between 30 and 63 points: Severe depressive symptoms	3 weeks