Behavioral and Neurophysiological Effects of Multichannel Executive Network tDCS Combined With Preferred Music Stimulation

Healthy Clinical Trial

Official title:

Behavioral and Neurophysiological Effects of Multichannel Executive Network tDCS Combined With Preferred Music Stimulation

Clinical Trial Details — Status: Recruiting

Administrative data

• NCT number: NCT04705532
• Other study ID #: 2014-280
• Status: Recruiting
• Phase: Phase 1
• Start date: October 4, 2019
• Est. completion date: December 30, 2021

Study information

• Verified date: October 2021
• Source: University of Liege
• Contact: Aurore Thibaut, PhD
• Phone: +3242843612
• Email: athibaut[@]uliege.be
• Is FDA regulated: No
• Study type: Interventional

Clinical Trial Summary

This study aims at comparing the effects of transcranial direct current stimulation combined with music on neurophysiological outcomes in healthy participants. This study also aims to evaluate the effects of tDCS combined with music on cognition.

Recruitment information / eligibility

• Status: Recruiting
• Enrollment: 24
• Est. completion date: December 30, 2021
• Est. primary completion date: December 30, 2021
• Accepts healthy volunteers: Accepts Healthy Volunteers
• Gender: All
• Age group: 18 Years to 40 Years

Eligibility

Inclusion Criteria:

• healthy adults

Exclusion Criteria:

• neurological disorders

• psychiatric disorders

• contra-indication to tDCS (eg, metallic brain implant, pacemaker)

• pregnancy

• alcool abuse

• active smoker

Related Conditions & MeSH terms

• Healthy

Intervention

Device:
• tDCS
Multi-channel tDCS will be applied over the executive network for 20 minutes at 4mA
• Sham tDCS
Sham tDCS will consist of applying the same parameters as for active but the corresponding device will be turned off after 30 seconds as to simulate the initial sensation of the active current. A current of 2mA will still be used (but turned off after 30 sec). The electrodes that will be used will be the same as for the active tDCS condition and the electrodes placement as well.

Other:
• Music
Subjects will listen to their preferred music for 20 minutes
• White noise
Subjects will listen to a white noise for 20 minutes

Locations

Country	Name	City	State
Belgium	University Hospital of Liege	Liege

Sponsors (1)

Lead Sponsor	Collaborator
University of Liege

Country where clinical trial is conducted

Belgium, 

Outcome

Type	Measure	Description	Time frame	Safety issue
Primary	3-back	The subject is presented with a sequence of stimuli, and the task consists of indicating when the current stimulus matches the one from 3 steps earlier in the sequence.	It will be measured over the course of four weeks
Secondary	Stroop	The subject has to name the font color of a printed word, while it can have a mismatch between the word and the color (ex: green is written in red).	It will be measured over the course of four weeks
Secondary	EEG - alpha power	Brain activity will be measured with an electroencephalography collected at rest. We will first look at the change in alpha power (8-12Hz)	It will be measured over the course of four weeks
Secondary	EEG - beta power	Brain activity will be measured with an electroencephalography collected at rest. We will also look at the change in other frequency bands (e.g., beta, theta, delta).	It will be measured over the course of four weeks