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Clinical Trial Summary

This study will investigate the impact of impaired renal function on the plasma pharmacokinetics of ALXN2050 in order to provide dosing recommendations for future indications in individuals with impaired renal function.


Clinical Trial Description

The study will initiate (Part 1) with participants with severe impaired renal function (Cohort 1) and their matched healthy control participants (Cohort 4). Following data review, the study may proceed (Part 2) with participants with moderate (Cohort 2) and mild (Cohort 3) impaired renal function if deemed necessary. ;


Study Design


Related Conditions & MeSH terms


NCT number NCT04623710
Study type Interventional
Source Alexion
Contact
Status Completed
Phase Phase 1
Start date July 8, 2021
Completion date March 21, 2022

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