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NCT04615611 Clinical Trial

Physiologic Performance Response to Salbutamol

Healthy Clinical Trial

Official title:
Individual beta2-adrenergic Performance Response to Salbutamol

Clinical Trial Details — Status: Not yet recruiting

Administrative data
NCT number NCT04615611
Other study ID # SAL-POWER
Secondary ID
Status Not yet recruiting
Phase N/A
First received
Last updated
Start date November 7, 2020
Est. completion date November 7, 2021

Study information
Verified date October 2020
Source University of Copenhagen
Contact n/a
Is FDA regulated No
Health authority
Study type Interventional

Clinical Trial Summary

This project aims to investigate the individual physiological response to beta2-adrenergic stimulation with salbutamol on performance-related outcomes

Recruitment information / eligibility
Status Not yet recruiting
Enrollment 20
Est. completion date November 7, 2021
Est. primary completion date November 7, 2021
Accepts healthy volunteers Accepts Healthy Volunteers
Gender All
Age group 18 Years to 45 Years
Eligibility Inclusion Criteria: - 18 to 45 years of age - Trained individuals with maximal oxygen uptake above 55 mL/kg/min for men and 50 mL/kg/min for women - Body mass index lower than 26 Exclusion Criteria: - Allergy towards study drug - Unacceptable side effects of the study drug - Chronic disease deemed by the MD to impose a risk or severely confound the study outcomes - Current smokers - Use of prescription medicine - Pregnancy

Study Design

Related Conditions & MeSH terms

Intervention

Drug:
• salbutamol
inhalation of salbutamol
• Placebo
administration of placebo

Locations
Country Name City State
n/a

Sponsors (1)
Lead Sponsor Collaborator
University of Copenhagen

Outcome
Type Measure Description Time frame Safety issue
Primary Sprint performance Power output during maximal cycling Measured ½ hour after drug administration
Secondary Muscle strength Quadriceps maximal voluntary contraction Measured ½ hour after drug administration
Secondary Sprint fatigue tolerance Fatigue index during maximal cycling Measured ½ hour after drug administration
Secondary Cycling endurance performance 4-min time trial on bike ergometer Measured ½ hour after drug administration
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