Healthy Clinical Trial
Official title:
Losartan Effects on the Emotion Processing in Humans
The aim of the study is to investigate the effect of losartan (50mg, single dose) on salience processing
In a double-blind, between-subject, placebo-controlled design the effects of a single dose of losartan (50mg) on salience processing in healthy participants will be examined. The study will adopt a previously validated visual Oddball fMRI paradigm, starting 90 minutes after subjects receive 50mg losartan or placebo. The task requires participants to respond to emotional and novelty oddballs. Neural activity will be assessed by the acquisition of functional magnetic resonance imaging (fMRI) data. ;
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